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Review
. 2024 Jul;10(7):584-587.
doi: 10.1016/j.trecan.2024.05.003. Epub 2024 Jun 4.

B7-H3: a robust target for immunotherapy in prostate cancer

Rafael Pulido  1 , José I López  2 , Caroline E Nunes-Xavier  3
Affiliations
Free article
Review

B7-H3: a robust target for immunotherapy in prostate cancer

Rafael Pulido et al. Trends Cancer. 2024 Jul.
Free article

Abstract

B7-H3, an immune checkpoint glycoprotein, facilitates immune evasion and the promotion of tumors and is highly expressed on the surface of prostate cancer (PCa) cells, which makes it a feasible and robust candidate for immunotherapies against advanced prostate cancer. Here, we summarize and discuss recent findings on the suitability of targeting B7-H3 in PCa treatment.

Keywords: B7-H3; immunotherapy; prostate cancer.

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Conflict of interest statement

Declaration of interests The authors have no interests to declare.

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