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. 2024 May 22:11:1391544.
doi: 10.3389/fmed.2024.1391544. eCollection 2024.

Development of the Korean Medicine Core Outcome Set for Facial Palsy: herbal medicine treatment of patients with facial palsy in primary clinics

Soo-Dam Kim #  1 , Sungha Kim #  1 , Mi Ju Son  1 , Jiyun Cha  2 , Pyung-Wha Kim  3 , Mi Mi Ko  1 , Soobin Jang  4 , Changsop Yang  1 , Myeong Soo Lee  1
Affiliations

Development of the Korean Medicine Core Outcome Set for Facial Palsy: herbal medicine treatment of patients with facial palsy in primary clinics

Soo-Dam Kim et al. Front Med (Lausanne). .

Abstract

Introduction: Facial palsy (FP) significantly affects the quality of life of patients and poses a treatment challenge in primary healthcare settings. This study aimed to develop a Korean medicine (KM) core outcome set (COS) for FP, with a focus on evaluating the effectiveness of herbal medicine (HM) treatments in KM primary clinics.

Methods: Outcomes and effect modifiers related to FP treatments were initially identified through related review articles. Subsequently, experts in the field took part in three rounds of modified Delphi consensus exercises to refine and prioritize these outcomes and effect modifiers. Additionally, primary KM clinicians were involved in a Delphi consensus round to assess the suitability and feasibility of the proposed COS in real-world clinical settings.

Results: The initial review of related literature identified 44 relevant studies, resulting in an initial selection of 23 outcomes and 10 effect modifiers. The expert consensus process refined these to 8 key outcomes and 6 effect modifiers, which established the foundation of the COS-FP-KM. Subsequently, primary KM clinicians confirmed the practicality and applicability of the COS, endorsing its suitability for use in KM primary clinics.

Conclusion: The COS-FP-KM establishes a standardized approach for assessing HM treatment effectiveness in FP patients in KM primary clinics. The COS-FP-KM encourages consistent outcome reporting and enhances patient care quality. Future work should aim to integrate broader stakeholder perspectives to refine and validate the COS further.

Keywords: Korean medicine; core outcome set; facial palsy; herbal medicine; primary care.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Figures

Figure 1
Figure 1
Flow chart of selection process. RCT, randomized controlled trial.
Figure 2
Figure 2
Overview of the consensus process during the three Delphi rounds in Phase 2. EMs, effect modifiers; SAQ, synkinesis assessment questionnaire; VAS, visual analog scale; NRS, numerical rating scale; MET, myoneural excitability test; DITI, digital infrared thermographic imaging; EMG, electromyography; ENoG, electroneurography; AST, aspartate transaminase; ALT, alanine transaminase; BUN, blood urea nitrogen; Cr, creatinine.
See this image and copyright information in PMC

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