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. 2024 Sep;46(9):2274-2283.
doi: 10.1002/hed.27835. Epub 2024 Jun 6.

Development of a plant-based surgical training model for fluorescence-guided cancer surgery

Mayu Shigeyama  1 , Naoki Nishio  1 , Akihisa Wada  1 , Sohei Mitani  2 , Gaku Morimoto  3 , Sayaka Yokoi  1 , Nobuaki Mukoyama  1 , Mai Yokoi  1 , Stan van Keulen  4 , Eben Rosenthal  5 , Michihiko Sone  1
Affiliations

Development of a plant-based surgical training model for fluorescence-guided cancer surgery

Mayu Shigeyama et al. Head Neck. 2024 Sep.

Abstract

Background: Fluorescence-guided surgery (FGS) can help surgeons to discriminate tumor tissue from adjacent normal tissues using fluorescent tracers.

Methods: We developed a surgical training model, manufactured using sustainable vegetable organic material with indocyanine green (ICG)-containing "tumor." Surgeons evaluated the model with both the closed-field and endoscopic fluorescence imaging devices and assessed its efficacy to identify residual tumor after enucleation using electrocautery.

Results: Strong correlations of fluorescence were obtained at all working distance (3, 5, 7, and 10 cm), showing the robustness of fluorescence signal for the closed-field and endoscopic fluorescence imaging devices. The higher fluorescence signals were obtained in the wound bed in the closed-field fluorescence imaging device and the residual tumor could be clearly identified by fluorescence endoscopy.

Conclusions: Our FGS training model may provide experience for surgeons unfamiliar with optical surgery and subsequent tissue interactions. The model seemed particularly helpful in teaching surgeons the principles of FGS.

Keywords: electrocautery; fluorescence endoscopy; fluorescence‐guided surgery; indocyanine green; surgical training.

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References

REFERENCES

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    1. Morimoto G, Kawahira H, Takayama S, Lefor AK. Chemical components of smoke produced from versatile training tissue models using electrocautery. Simul Healthc. 2022;17(1):29‐34.

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