RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes
- PMID: 388428
- PMCID: PMC413086
- DOI: 10.1073/pnas.76.10.5095
RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes
Abstract
Cloned human DNA fragments containing globin genes are transcribed in vitro to form discrete RNA species. One transcription unit is located approximately 1500 base pairs upstream from the G-gamma-globin gene. This transcript is partially homologous to a polymerase III template located approximately 1000 base pairs upstream from the delta-globin gene and to DNA located a short distance downstream from the beta-globin gene.
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