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Review
. 2024 Aug 1;144(2):e35-e39.
doi: 10.1097/AOG.0000000000005638. Epub 2024 Jun 6.

Ectopic Prostatic Tissue in Female Urethral Diverticulum

Annika Sinha  1 , Sarah Cantrell, Diana M Kozman, J Eric Jelovsek
Affiliations
Review

Ectopic Prostatic Tissue in Female Urethral Diverticulum

Annika Sinha et al. Obstet Gynecol. .

Abstract

Background: Ectopic prostatic tissue in female patients is rare. It is theorized that the presence of prostatic tissue in female patients is likely a Wolffian remnant or transformation of hormonally mediated tissue of the uterus, cervix, Skene's gland, and, rarely, periurethral tissue. Due to the increase in the use of testosterone and gender-affirming therapies, it is important to understand the role of testosterone in mediating the presence of ectopic prostatic tissue.

Case: We present a case of ectopic prostatic tissue in a urethral diverticulum in a female patient with exposure to testosterone hormone therapy and review the literature on this finding.

Conclusion: Although rare, ectopic prostatic tissue should be considered in the differential diagnosis of anterior vaginal cysts, especially in the setting of testosterone supplementation.

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Conflict of interest statement

Financial Disclosure J. Eric Jelovsek reports money was paid to his institution from the NIDDK, FDA, and the NICHD. He received payment from UpToDate. He participates in an advisory board for Collamedix. The other authors did not report any potential conflicts of interest.

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