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Review
. 1985 Jan:15 Suppl A:293-6.
doi: 10.1093/jac/15.suppl_a.293.

Effects of sub-bactericidal concentrations of antibiotics in experimental models of endocarditis

T A Drake, W M Scheld, M A Sande
Review

Effects of sub-bactericidal concentrations of antibiotics in experimental models of endocarditis

T A Drake et al. J Antimicrob Chemother. 1985 Jan.

Abstract

Subinhibitory and sub-bactericidal concentrations of antibiotics significantly influence host-bacterial interactions. This paper reviews the pathogenesis of endocarditis and examines how subinhibitory concentrations of antibiotics may influence the course of the disease. At present significant effects have been documented only for the stage of bacterial adherence to the damaged valve.

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