Pulmonary Embolism in Donor Lungs-Incidence and Management
- PMID: 38846992
- PMCID: PMC11152617
- DOI: 10.1055/s-0044-1782536
Pulmonary Embolism in Donor Lungs-Incidence and Management
Abstract
In efforts to decrease the mortality on the waiting list for lung transplantation, alternatives to increase the donor pool have been explored. Caution must be used when accepting donor lungs with pulmonary embolism (PE), as prior evidence has shown mixed results after transplantation of donor lungs with PE. However, the mere diagnosis of PE on imaging should not be the sole reason for the exclusion of these donors for transplant, and they should be reviewed as any other donor. A comprehensive evaluation should be performed for every donor, with a special focus on abnormalities of gas exchange and gross pathologic characteristics during procurement.
Keywords: deep vein thrombosis; embolectomy; pulmonary embolism; surgery; thrombectomy; thrombolysis; transplant.
International College of Angiology. This article is published by Thieme.
Conflict of interest statement
Conflict of Interest None declared.
Similar articles
-
Transplantation of donor lungs with pulmonary embolism - a retrospective study.Transpl Int. 2019 Jun;32(6):658-667. doi: 10.1111/tri.13407. Epub 2019 Feb 21. Transpl Int. 2019. PMID: 30712278
-
The implications of pulmonary embolism in a multiorgan donor for subsequent pulmonary, renal, and cardiac transplantation.J Heart Lung Transplant. 2008 Jan;27(1):78-85. doi: 10.1016/j.healun.2007.10.001. J Heart Lung Transplant. 2008. PMID: 18187091
-
High prevalence of pulmonary arterial thrombi in donor lungs rejected for transplantation.J Heart Lung Transplant. 2005 Oct;24(10):1650-6. doi: 10.1016/j.healun.2004.11.011. J Heart Lung Transplant. 2005. PMID: 16210143
-
Pulmonary Embolism Following Lung Transplantation: Prevention and Management.Int J Angiol. 2024 May 13;33(2):123-127. doi: 10.1055/s-0044-1786859. eCollection 2024 Jun. Int J Angiol. 2024. PMID: 38846988 Free PMC article. Review.
-
Percutaneous Management of High-Risk Pulmonary Embolism.Circ Cardiovasc Interv. 2023 Feb;16(2):e012166. doi: 10.1161/CIRCINTERVENTIONS.122.012166. Epub 2023 Feb 6. Circ Cardiovasc Interv. 2023. PMID: 36744463 Review.
References
-
- McCurry K R. Brief overview of lung, heart, and heart-lung transplantation. Crit Care Clin. 2019;35(01):1–9. - PubMed
-
- Valapour M, Lehr C J, Skeans M A et al.OPTN/SRTR 2016 Annual Data Report: lung. Am J Transplant. 2018;18 01:363–433. - PubMed
-
- Egan T M, Murray S, Bustami R Tet al.Development of the new lung allocation system in the United States Am J Transplant 20066(5 Pt 2):1212–1227. - PubMed
-
- Valapour M, Lehr C J, Wey A, Skeans M A, Miller J, Lease E D. Expected effect of the lung composite allocation score system on US lung transplantation. Am J Transplant. 2022;22(12):2971–2980. - PubMed
-
- Kahan E S, Petersen G, Gaughan J P, Criner G J. High incidence of venous thromboembolic events in lung transplant recipients. J Heart Lung Transplant. 2007;26(04):339–344. - PubMed
Publication types
LinkOut - more resources
Full Text Sources