Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2024 Jun 7:104:adv40377.
doi: 10.2340/actadv.v104.40377.

An Asymptomatic Brown Plaque on the Face: A Quiz

Daoning Zhang  1 , Pingping Lin  1 , Hang Li  2
Affiliations
Case Reports

An Asymptomatic Brown Plaque on the Face: A Quiz

Daoning Zhang et al. Acta Derm Venereol. .
No abstract available

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Clinical appearance and dermoscopy. (a) A 10 x 6 mm flat brown indurated plaque on the left cheek, with ill-defined border. (b) Dermoscopy revealed pigmented network (white arrow) and linear streak (black arrow).
Fig. 2
Fig. 2
Histology and immunohistochemistry findings. (a) Large amounts of spindle-shaped cells interlaced and proliferated in the middle and lower fat lobules of the dermis (haematoxylin-eosin; scale bar=2.5mm). (b) Spindle-shaped cells parallel to the surface.(haematoxylin-eosin; scale bar=250 μm) (c) Spindle-shaped cells with large nuclei (black arrow; scale bar=50 μm). (d) Immunohistochemistry showed SMA-positive cells (anti-SMA; scale bar=250μm) (e–f) Immunohistochemistry showed CD34 negative cells (anti-CD34; (e) scale bar=2.5mm and (f) scale bar=250 μm). (g) Immunohistochemistry showed Factor XIII-positive cells (anti-factor XIII; scale bar=250 μm). (h) Immunohistochemistry showed S-100-negative cells (anti-S100; scale bar=250 μm). (i) Immunohistochemistry showed Ki-67-negative cells (anti-Ki67; scale bar=250 μm).
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Gomez-Moyano E, Vera-Casano A, Martinez-Garcia S, Sanz-Trelles A, Crespo-Erchiga V. Two cases of dermatomyofibroma (plaque-like dermal fibromatosis). Int J Dermatol 2010; 49: 914–917. - PubMed
    1. Mentzel T, Kutzner H. Dermatomyofibroma: clinicopathologic and immunohistochemical analysis of 56 cases and reappraisal of a rare and distinct cutaneous neoplasm. Am J Dermatopathol 2009; 31: 44–49. - PubMed
    1. Fu S, Zhang J, Zhan Y, Zhang H, Herman EI, Lu Q, et al. . A rare case report for dermatomyofibroma in nasion. Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018; 43: 1037–1040. - PubMed
    1. Campagnolo OA, Morais CF, Ughini MO, Aoki CM, Menegazzo M. Dermatomyofibroma. An Bras Dermatol 2017; 92: 101–103. - PMC - PubMed
    1. Yamamoto T. Dermatofibroma: a possible model of local fibrosis with epithelial/mesenchymal cell interaction. J Eur Acad Dermatol Venereol 2009; 23: 371–375. - PubMed

Publication types

LinkOut - more resources