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Editorial
. 2024 Aug;13(8):e240091.
doi: 10.57264/cer-2024-0091. Epub 2024 Jun 8.

Why is target trial emulation not being used in health technology assessment real-world data submissions?

Alejandra Castanon  1 , Stephen Duffield  2 , Sreeram Ramagopalan  1 , Robert Reynolds  3
Affiliations
Editorial

Why is target trial emulation not being used in health technology assessment real-world data submissions?

Alejandra Castanon et al. J Comp Eff Res. 2024 Aug.
No abstract available

Keywords: health technology assessment; observational data; randomized controlled trials; real-world data; target trial emulation.

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Conflict of interest statement

Competing interests disclosure

The authors have no competing interests or relevant affiliations with any organization or entity with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

Figures

Figure 1.
Figure 1.. Peer reviewed publications mentioning target trial emulation.
Based on a search conducted on 17 May 2024 using the following terms: ‘target trial’ OR ‘target trial emulation’ OR ‘trial emulation’.
See this image and copyright information in PMC

Comment on

References

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    1. Hernán MA, Robins JM. Using big data to emulate a target trial when a randomized trial is not available. Am. J. Epidemiol. 183, 758–764 (2016). - PMC - PubMed
    1. Dickerman BA, García-Albéniz X, Logan RW, Denaxas S, Hernán MA. Evaluating metformin strategies for cancer prevention: a target trial emulation using electronic health records. Epidemiology 34, 690 (2023). - PMC - PubMed
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    1. Khurana V, Bejjanki HR, Caldito G, Owens MW. Statins reduce the risk of lung cancer in humans: a large case-control study of US veterans. Chest 131, 1282–1288 (2007). - PubMed

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