A high prevalence of hereditary alpha-tryptasemia in pediatric mastocytoma

M Madrange¹, J Rossignol^{1

2}, C Devin¹, L Bekel³, N Bellon³, A Welfringer-Morin³, C Méni³, J Bonigen³, P Bataille³, C Burdet⁴, J Agopian^{5

6}, P Dubreuil^{5

6}, O Hermine^{1

2

6}, C Bodemer^{1

3}, L Polivka^{1

3}; CEREMAST network

Affiliations

¹ CEREMAST, Imagine Institute, INSERM U1163, AP-HP, Necker-Children's Hospital, Paris Centre University, Paris, France.
² Department of Hematology, Necker-Children's Hospital, AP-HP, Paris Centre University, Paris, France.
³ Department of Dermatology, Reference Center for Rare Skin disorders in Children, AP-HP, Necker-Children's Hospital, Paris Centre University, Paris, France.
⁴ Centre d'Investigation Clinique, Inserm CIC 1425, AP-HP, Bichat Hospital, Paris Centre University, Paris, France.
⁵ Centre de Recherche en Cancérologie de Marseille, INSERM U1068, Marseille, France.
⁶ Association Française pour les Initiatives de Recherche sur le Mastocyte et les Mastocytoses (AFIRMM), Marseille, France.

M Madrange et al. Allergy. 2024 Nov.

. 2024 Nov;79(11):3129-3132.

doi: 10.1111/all.16185. Epub 2024 Jun 8.

¹ CEREMAST, Imagine Institute, INSERM U1163, AP-HP, Necker-Children's Hospital, Paris Centre University, Paris, France.
² Department of Hematology, Necker-Children's Hospital, AP-HP, Paris Centre University, Paris, France.
³ Department of Dermatology, Reference Center for Rare Skin disorders in Children, AP-HP, Necker-Children's Hospital, Paris Centre University, Paris, France.
⁴ Centre d'Investigation Clinique, Inserm CIC 1425, AP-HP, Bichat Hospital, Paris Centre University, Paris, France.
⁵ Centre de Recherche en Cancérologie de Marseille, INSERM U1068, Marseille, France.
⁶ Association Française pour les Initiatives de Recherche sur le Mastocyte et les Mastocytoses (AFIRMM), Marseille, France.

No abstract available

References

1. Polivka L, Rossignol J, Neuraz A, et al. Criteria for the regression of pediatric Mastocytosis: a long‐term follow‐up. J Allergy Clin Immunol Pract. 2020;9:1695‐1704.e5. doi:10.1016/j.jaip.2020.12.019
1. Valent P, Akin C, Metcalfe DD. Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts. Blood. 2017;129:1420‐1427.
1. Valent P, Horny HP, Escribano L, et al. Diagnostic criteria and classification of mastocytosis: a consensus proposal. Leuk Res. 2001;25:603‐625.
1. Valent P, Akin C, Escribano L, et al. Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria. Eur J Clin Investig. 2007;37:435‐453.
1. Lyons JJ, Yu X, Hughes JD, et al. Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number. Nat Genet. 2016;48:1564‐1569.