Dermatologic fungal neglected tropical diseases-Part II. Management and morbidity

Abstract

In this part 2 of a 2-part continuing medical education series, the management, outcomes, and morbidities for fungal skin neglected tropical diseases (NTDs), including eumycetoma, chromoblastomycosis, paracoccidioidomycosis, sporotrichosis, emergomycosis, talaromycosis, and lobomycosis are reviewed. While fungal skin NTDs are associated with poverty in resource-limited settings, they are more often associated with immunosuppression and global migration in the United States. These infections have a high morbidity burden, including disfigurement, physical disability, coinfection, malignant transformation, mental health issues, and financial impact. For most fungal skin NTDs, management is difficult and associated with low cure rates. Dermatologists play a central role in initiating appropriate treatment early in disease course in order to improve patient outcomes.

Keywords: chromoblastomycosis; emergomycosis; endemic mycoses; eumycetoma; fungal infections; implantation mycoses; lobomycosis; neglected tropical diseases; outcomes; paracoccidioidomycosis; sporotrichosis; systemic mycoses; talaromycosis; therapeutics.