Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Jun 10;8(1):57.
doi: 10.1186/s41687-024-00738-4.

Translation and reliability and validity of the Chinese version of Amyotrophic Lateral Sclerosis-Specific Quality of Life-Short Form

Zhijie Zhang  1 , Xin He  1   2 , Jialu Cui  1 , Jing Wang  1 , Baoxin Shi  3
Affiliations

Translation and reliability and validity of the Chinese version of Amyotrophic Lateral Sclerosis-Specific Quality of Life-Short Form

Zhijie Zhang et al. J Patient Rep Outcomes. .

Abstract

Objective: To translate Amyotrophic Lateral Sclerosis-Specific Quality of Life-Short Form (ALSSQOL-SF) and test its reliability and validity, so that explore feasibility in Chinese mainland and make up the gap of specific tools for measuring quality of life of patients with ALS.

Methods: This was a cross-sectional design. The Brislin translation model was used to translate ALSSQOL-SF, and the Chinese version of ALSSQOL-SF (C-ALSSQOL-SF) was revised through cultural adaptation and pre-test. The convenience sampling method was used to investigate 138 patients with ALS in Tianjin to test the reliability and validity of the C-ALSSQOL-SF.

Results: The C-ALSSQOL-SF included 20 items, covering 6 dimensions: physical symptoms, bulbar function, negative emotion, interaction with people and the environment, religiosity and intimacy. The scale-level content validity index (S-CVI) of C-ALSSQOL-SF was 0.964, and the item-level content validity index (I-CVI) was between 0.857 to 1.000. The results of Confirmatory Factor Analysis (CFA) showed that CMIN/DF = 1.161, RMSEA = 0.034, GFI = 0.892, IFI = 0.976, TLI = 0.969, CFI = 0.975, and the 6-factor model fitted well. The scores of C-ALSSQOL-SF and WHOQOL-BREF were positively correlated (r = 0.745). The Cronbach's α coefficient of the scale was 0.85, the Cronbach's α coefficient of each dimension was between 0.59 to 0.86, and the split-half reliability was 0.78.

Conclusion: The Chinese version of ALSSQOL-SF has good reliability and validity, and can be used as a tool to evaluate the quality of life of patients with ALS in Chinese mainland.

Keywords: Amyotrophic lateral sclerosis; Chinese adaptation; Quality of life; Reliability; Scale; Validity.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest.

Figures

Fig. 1
Fig. 1
Modified model diagram
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Feldman EL, Goutman SA, Petri S, Mazzini L, Savelieff MG, Shaw PJ, et al. Amyotrophic lateral sclerosis. Lancet. 2022;400(10360):1363–1380. doi: 10.1016/S0140-6736(22)01272-7. - DOI - PMC - PubMed
    1. Amyotrophic lateral sclerosis collaboration Group, Chinese Society of Neurology (2022) Expert consensus on diagnosis and treatment of amyotrophic lateral sclerosis in China 2022. Chin J Neurol 55(06):581–588
    1. Zhang J, Liu XQ, Liang HT, Xu SY, Wang XH, Xu RS. Amyotrophic lateral sclerosis in seven provinces of Chinese mainland: a cross-sectional survey from 2015 to 2016. Front Aging Neurosci. 2022;14:946353. doi: 10.3389/fnagi.2022.946353. - DOI - PMC - PubMed
    1. Fong GC, Cheng TS, Lam K, Cheng WK, Mok KY, Cheung CM, et al. An epidemiological study of motor neuron disease in Hong Kong. Amyotroph Lateral Scler Other Motor Neuron Disord. 2005;6(3):164–168. doi: 10.1080/14660820510028412a. - DOI - PubMed
    1. Tsai CP, Wang KC, Hwang CS, Lee IT, Lee CT. Incidence, prevalence, and medical expenditures of classical amyotrophic lateral sclerosis in Taiwan, 1999–2008. J Formos Med Assoc. 2015;114(7):612–619. doi: 10.1016/j.jfma.2013.01.008. - DOI - PubMed