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. 2024 Jun 3;7(6):e2415917.
doi: 10.1001/jamanetworkopen.2024.15917.

Phoenix Sepsis Score and Risk of Attributable Mortality in Children With Cancer

Joshua Wolf  1 , Zachary Rubnitz  2 , Asya Agulnik  3 , Jose Ferrolino  1 , Yilun Sun  4 , Li Tang  4
Affiliations

Phoenix Sepsis Score and Risk of Attributable Mortality in Children With Cancer

Joshua Wolf et al. JAMA Netw Open. .
No abstract available

Plain language summary

This prognostic study analyzes the accuracy of the Phoenix Sepsis Score for the classification of attributable mortality risk in children with cancer presenting to the intensive care.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Wolf reported receiving support from Karius Inc, the Pediatric Infectious Diseases Society, Scynexis, and Merck, receiving grants from Pfizer, and having a patent pending for cell-free DNA prediction of infection outside the submitting work. Dr Tang reported receiving grants from the National Cancer Institute and the American Lebanese Syrian Charities outside the submitted work. No other disclosures were reported.

Figures

Figure.
Figure.. Performance of Phoenix Sepsis Score and Comparators for Prediction of Adverse Outcomes in Children With Cancer Admitted to the Intensive Care Unit With Suspected Infection
PHO-Phoenix was the Phoenix Sepsis Score calculated excluding platelet count to account for possible confounding by chemotherapy-related thrombocytopenia. AUC indicates area under the curve; PELOD2, Paediatric Logistic Organ Dysfunction 2; PRISM3, Pediatric Risk of Mortality 3; pSOFA, Pediatric Sequential Organ Failure Assessment; qSOFA, quick SOFA.
See this image and copyright information in PMC

References

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    1. Sanchez-Pinto LN, Bennett TD, DeWitt PE, et al. ; Society of Critical Care Medicine Pediatric Sepsis Definition Task Force . Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock. JAMA. 2024;331(8):675-686. doi:10.1001/jama.2024.0196 - DOI - PMC - PubMed
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