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Editorial
. 2024 Jun 11;149(24):1899-1902.
doi: 10.1161/CIRCULATIONAHA.124.069446. Epub 2024 Jun 10.

A Concept of "Athero-Oncology": Tumor-Like Smooth Muscle Cells Drive Atherosclerosis

Payel Chatterjee  1 , Kathleen A Martin  1
Affiliations
Editorial

A Concept of "Athero-Oncology": Tumor-Like Smooth Muscle Cells Drive Atherosclerosis

Payel Chatterjee et al. Circulation. .
No abstract available

Keywords: Editorials; atherosclerosis; myocytes, smooth muscle; neoplasms.

PubMed Disclaimer

Conflict of interest statement

Disclosures None.

Figures

Figure 1
Figure 1. Comparison of SMC-derived cells (SDCs) and cancer cells.
Text in the circle indicates shared risk factors and common features between SDCs in atherosclerotic plaques and tumor cells. Boxes at bottom left (SDCs) and right (cancer cells) indicate features unique to each condition. Lineage tracing reveals that SMC-derived cells in plaques are clonal –, but whether this clonality arises from SMC mutations remains an important question for further study.
See this image and copyright information in PMC

Comment on

  • Atherosclerosis Is a Smooth Muscle Cell-Driven Tumor-Like Disease.
    Pan H, Ho SE, Xue C, Cui J, Johanson QS, Sachs N, Ross LS, Li F, Solomon RA, Connolly ES Jr, Patel VI, Maegdefessel L, Zhang H, Reilly MP. Pan H, et al. Circulation. 2024 Jun 11;149(24):1885-1898. doi: 10.1161/CIRCULATIONAHA.123.067587. Epub 2024 Apr 30. Circulation. 2024. PMID: 38686559 Free PMC article.

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