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Comment
. 2024 Jul;23(7):498.
doi: 10.1038/d41573-024-00097-1.

A route to small-molecule Lp(a) inhibitors for heart disease

Isobel Leake
Comment

A route to small-molecule Lp(a) inhibitors for heart disease

Isobel Leake. Nat Rev Drug Discov. 2024 Jul.
No abstract available

Keywords: Cardiovascular biology; Chemistry; Drug discovery; Structural biology.

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Comment on

  • Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
    Diaz N, Perez C, Escribano AM, Sanz G, Priego J, Lafuente C, Barberis M, Calle L, Espinosa JF, Priest BT, Zhang HY, Nosie AK, Haas JV, Cannady E, Borel A, Schultze AE, Sauder JM, Hendle J, Weichert K, Nicholls SJ, Michael LF. Diaz N, et al. Nature. 2024 May;629(8013):945-950. doi: 10.1038/s41586-024-07387-z. Epub 2024 May 8. Nature. 2024. PMID: 38720069 Free PMC article.

References

    1. Daiz, N. et al. Discovery of potent small-molecule inhibitors of lipoprotein(a) formation. Nature 629, 945–950 (2024) - PubMed - DOI

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