Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Jul-Sep;47(3):243-256.
doi: 10.1097/CNQ.0000000000000513. Epub 2024 Jun 7.

Cardiogenic Shock: An Overview

Affiliations
Review

Cardiogenic Shock: An Overview

Mohamed Toufic El Hussein et al. Crit Care Nurs Q. 2024 Jul-Sep.

Abstract

Cardiogenic shock (CS) is a complex and dreadful condition for which effective treatments remain unclear. The concerningly high mortality rate of CS emphasizes a need for developing effective therapies to reduce its mortality and reverse its detrimental course. This article aims to provide an updated and evidence-based review of the pathophysiology of CS and the related pharmacotherapeutics with a special focus on vasoactive and inotropic agents.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest in the manuscript, including financial, consultant, institutional, and other relationships that might lead to bias or a conflict of interest.

References

    1. Kislitsina ON, Rich JD, Wilcox JE, Pham DT, Churyla A, Vorovich EB, Ghafourian K, Yancy CW. Shock – classification and pathophysiological principles of therapeutics. Curr Cardiol Rev. 2019;15(2):102-113. doi:10.2174/1573403X15666181212125024. - DOI
    1. Schrage B, Becher PM, Goßling A, Savarese G, Dabboura S, Yan I, Beer B, Söffker G, Seiffert M, Kluge S, Kirchhof P, Blankenberg S, Westermann D. Temporal trends in incidence, causes, use of mechanical circulatory support and mortality in cardiogenic shock. ESC Heart Fail. 2021;8(2):1295-1303. doi:10.1002/ehf2.13202. - DOI
    1. Zeymer U, Bueno H, Granger CB, Hochman J, Huber K, Lettino M, Price S, Schiele F, Tubaro M, Vranckx P, Zahger D, Thiele H. Acute cardiovascular care association position statement for the diagnosis and treatment of patients with acute myocardial infarction complicated by cardiogenic shock: a document of the acute cardiovascular care association of the European Society of Cardiology. Eur Heart J. 2020;9(2):183-197. doi:10.1177/2048872619894254. - DOI
    1. Vincent J-L, De Backer D. Circulatory shock. N Engl J Med. 2013;369(18):1726-1734. doi:10.1056/NEJMra1208943. - DOI
    1. de Chambrun MP, Donker DW, Combes A. What’s new in cardiogenic shock? Intensive Care Med. 2020;46(5):1016-1019. doi:10.1007/s00134-020-05973-z. - DOI

MeSH terms

LinkOut - more resources