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Case Reports
. 2024 Oct;17(5):928-935.
doi: 10.1007/s12328-024-02001-1. Epub 2024 Jun 11.

A case of ulcerative colitis with a variety of autoimmune diseases including ankylosing spondylitis, type 2 autoimmune pancreatitis, and primary sclerosing cholangitis

Marie Kurebayashi  1 , Akira Hashimoto  2 , Mizuki Kawachi  2 , Shoma Sawai  2 , Takahiro Ono  2 , Yuichi Tahara  2 , Naoki Kuroda  2 , Naohiko Yoshizawa  2 , Hiroyuki Fuke  2 , Atsuya Shimizu  2
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Case Reports

A case of ulcerative colitis with a variety of autoimmune diseases including ankylosing spondylitis, type 2 autoimmune pancreatitis, and primary sclerosing cholangitis

Marie Kurebayashi et al. Clin J Gastroenterol. 2024 Oct.

Abstract

Ankylosing spondylitis (AS), primary sclerosing cholangitis (PSC), and autoimmune pancreatitis (AIP) are known as extraintestinal manifestations (EIMs) of ulcerative colitis (UC). A 74-year-old Japanese man visited our hospital because of white stool. He had been diagnosed with AS when he was 30 years old, and he was HLA-B27-positive. Based on various examination results, it was suspected that AIP had caused bile duct stricture. During the clinical course, he was diagnosed with UC and PSC. Then, AIP was diagnosed because he had localized pancreatic enlargement, irregular stenosis of the main pancreatic duct, PSC, and no tumor cells of pancreas. A patient with all four of these diseases, AS, AIP, PSC, and UC, is very rare. Therefore, we report a quite rare case with three EIMs (AS, PSC, and AIP) of UC.

Keywords: Ankylosing spondylitis; Extraintestinal manifestations; Primary sclerosing cholangitis; Type 2 autoimmune pancreatitis; Ulcerative colitis.

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References

    1. Pitchumoni CS, Rubin A, Das K, et al. Pancreatitis in inflammatory bowel diseases. J Clin Gastroenterol. 2010;44:246–53. - DOI - PubMed
    1. Garber A, Regueiro M. Extraintestinal manifestations of inflammatory bowel disease: epidemiology, etiopathogenesis, and management. Curr Gastroenterol Rep. 2019. https://doi.org/10.1007/s11894-019-0698-1 . - DOI - PubMed
    1. Vavricka SR, Schoepfer A, Scharl M, et al. Extraintestinal manifestations of inflammatory bowel disease. Inflamm Bowel Dis. 2015;21:1982–92. - DOI - PubMed
    1. Su CG, Judge TA, Lichtenstein GR, et al. Extraintestinal manifestations of inflammatory bowel disease. Gastroenterol Clin North Am. 2002;31:307–27. - DOI - PubMed
    1. Vavricka SR, Rogler G, Gantenbein C, et al. Chronological order of appearance of extraintestinal manifestations relative to the time of IBD diagnosis in the Swiss inflammatory bowel disease cohort. Inflamm Bowel Dis. 2015;21:1794–800. - DOI - PubMed

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