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Book

Normal and Abnormal Complete Blood Count With Differential

Jason El Brihi  1 , Surabhi Pathak  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan.
.
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Free Books & Documents
Book

Normal and Abnormal Complete Blood Count With Differential

Jason El Brihi et al.
Free Books & Documents

Excerpt

The complete blood count (CBC) is one of the most commonly performed laboratory investigations in medicine and provides information regarding circulating blood cell size and quantity. The standard CBC includes a measured red cell count (RBC), hemoglobin (Hb), and hematocrit (Hct), calculated red cell indices, a platelet count, and a white cell count (WBC). Most analyzers now also automatically generate a leucocyte differential.

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Conflict of interest statement

Disclosure: Jason El Brihi declares no relevant financial relationships with ineligible companies.

Disclosure: Surabhi Pathak declares no relevant financial relationships with ineligible companies.

References

    1. Tefferi A, Hanson CA, Inwards DJ. How to interpret and pursue an abnormal complete blood cell count in adults. Mayo Clin Proc. 2005 Jul;80(7):923-36. - PMC - PubMed
    1. Cappellini MD, Motta I. Anemia in Clinical Practice-Definition and Classification: Does Hemoglobin Change With Aging? Semin Hematol. 2015 Oct;52(4):261-9. - PubMed
    1. Guideline on haemoglobin cutoffs to define anaemia in individuals and populations [Internet] World Health Organization; Geneva: 2024. - PubMed
    1. Gulati G, Uppal G, Gong J. Unreliable Automated Complete Blood Count Results: Causes, Recognition, and Resolution. Ann Lab Med. 2022 Sep 01;42(5):515-530. - PMC - PubMed
    1. Turner J, Parsi M, Badireddy M. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2023. Aug 8, Anemia.

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