Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1985 Feb;18(1):3-13.
doi: 10.1016/s0009-9120(85)80016-3.

Abnormalities of serum and plasma components in patients with multiple sclerosis

H C Ford
Review

Abnormalities of serum and plasma components in patients with multiple sclerosis

H C Ford. Clin Biochem. 1985 Feb.

Abstract

Qualitative and quantitative abnormalities in protein and non-protein components of serum and plasma in patients with multiple sclerosis have been the subjects of numerous reports. In this review many of the more recent observations are documented and evaluated. It is concluded that at present the welter of information that has been gathered does not contribute in any major, coherent way to our understanding of the etiology or pathogenesis of the disorder. Several of the abnormalities that have been observed may be future candidates for biochemical markers for multiple sclerosis; at present none is sufficiently reliable, distinctive or easily performed to warrant the status of a useful diagnostic or prognostic test.

PubMed Disclaimer

References

    1. Iivanainen MV. The significance of abnormal immune responses in patients with multiple sclerosis. J Neuroimmunol. 1981;1:141–172. - PubMed
    1. Rathke E, Jones M. Serum cerebrosides in multiple sclerosis. J Neurochem. 1974;22:311–313. - PubMed
    1. Samuelson K. Separation and identification of cerebrosides in cerebrospinal fluid by gas chromatography—mass spectrometry. Scand J Clin Lab Invest. 1971;27:381–391. - PubMed
    1. Tourtellotte WW, Haerer AF. Lipids in cerebrospinal fluid. XII. In multiple sclerosis and retrobulbar neuritis. Arch Neurol. 1969;20:605–615. - PubMed
    1. Vincent B, Jones M. Plasma cerebrosides in stroke and multiple sclerosis. Ann Clin Lab Sci. 1975;5:45–51. - PubMed