Mapping myeloid cell function: Spatial diversity in tumor and neuronal microenvironment
- PMID: 38861929
- DOI: 10.1016/j.ccell.2024.05.018
Mapping myeloid cell function: Spatial diversity in tumor and neuronal microenvironment
Abstract
In this issue of Cancer Cell, Zhong et al. explore the dual role of TREM2 in glioblastoma-associated myeloid cells, demonstrating its function in promoting inflammation at the tumor-neural interface and suppression within the tumor core, influenced by the local microenvironment. These findings open up promising prospects for advancements in neuro-oncological immunotherapy.
Copyright © 2024 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
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