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. 2024 May 28:11:1394055.
doi: 10.3389/fvets.2024.1394055. eCollection 2024.

The use of platelet rich plasma in the treatment of degenerative joint disease in cats: an exploratory case series

Janice Huntingford  1 , Andrea Looney  2 , James Johnson  3 , Lisa Miller  3
Affiliations

The use of platelet rich plasma in the treatment of degenerative joint disease in cats: an exploratory case series

Janice Huntingford et al. Front Vet Sci. .

Abstract

Objective: To evaluate the effectiveness of intra-articular autologous Platelet Rich Plasma (PRP) in managing Degenerative Joint Disease (DJD) in cats.

Design: Prospective pilot clinical trial.

Methods: Six domestic cats with clinically and radiographically diagnosed DJD received intra-articular injections of autologous PRP. Clinical assessments pre and post intra-articular injections were conducted using the Feline Musculoskeletal Pain Index (FMPI, owner assessed) and Visual Analog Scale (VAS, clinician assessed) at baseline, Day 14, Day 28, and Day 42-45.

Results: Significant improvements were noted in both FMPI and VAS scores at the end of the study period, indicating enhanced joint function and reduced pain.

Conclusion and clinical relevance: The study suggests the potential of PRP therapy as a safe and effective treatment for feline DJD, warranting further research with larger cohorts and longer follow-up to establish comprehensive treatment guidelines.

Keywords: degenerative joint disease (DJD); feline; osteoarthritis; platelet rich plasma (PRP); regenerative medicine.

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Conflict of interest statement

JJ and LM are employees of the company who manufactures the CRT PRP system used in this work. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
(A) FMPI questions 1–17 scoring and (B) FMPI questions 1–17%possible score.
Figure 2
Figure 2
(A) FMPI questions 1–19 scoring and (B) FMPI questions 1–19%possible score.
Figure 3
Figure 3
Clinician visual analog scale (VAS) results.
See this image and copyright information in PMC

References

    1. Lascelles BDX. Feline degenerative joint disease. Vet Surg. (2010) 39:2–13. doi: 10.1111/j.1532-950X.2009.00597.x - DOI - PubMed
    1. Gunew MN, Menrath VH, Marshall RD. Long-term safety, efficacy and palatability of oral meloxicam at 0.01-0.03 mg/kg for treatment of osteoarthritic pain in cats. J Feline Med Surg. (2008) 10:235–41. doi: 10.1016/j.jfms.2007.10.007, PMID: - DOI - PMC - PubMed
    1. Lascelles BD, Hansen BD, Roe S, Depuy V, Thomson A, Pierce CC, et al. . Evaluation of client-specific outcome measures and activity monitoring to measure pain relief in cats with osteoarthritis. J Vet Intern Med. (2007) 21:410–6. doi: 10.1111/j.1939-1676.2007.tb02983.x PMID: - DOI - PubMed
    1. Kurnaz R, Balta O. Effect of platelet-rich plasma and platelet-rich fibrin matrix on healing of vertical meniscal tears in a rabbit model. Acta Orthop Traumatol Turc. (2020) 54:186–95. doi: 10.5152/j.aott.2020.02.20, PMID: - DOI - PMC - PubMed
    1. Li Z, Weng X. Platelet-rich plasma use in meniscus repair treatment: a systematic review and meta-analysis of clinical studies. J Orthop Surg Res. (2022) 17:446. doi: 10.1186/s13018-022-03293-0, PMID: - DOI - PMC - PubMed