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Case Reports
. 2024 Apr 30:24:QA14.
eCollection 2024.

Leukoplakia of the Lower Lip Reconstructed With a Tongue Flap

Sakurako Kunieda  1   2 , Kenji Suzuki  1 , Syunya Tamamine  1 , Atsuyuki Kuro  1 , Michika Fukui  2 , Natsuko Kakudo  2
Affiliations
Case Reports

Leukoplakia of the Lower Lip Reconstructed With a Tongue Flap

Sakurako Kunieda et al. Eplasty. .
No abstract available

Keywords: Leukoplakia; Lower Lip; Reconstruction; Tongue Flap.

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Conflict of interest statement

Disclosures: The authors disclose no financial or other conflicts of interest.

Figures

Figure 1
Figure 1
A homogeneous white plaque (35 × 5 mm) on the lower lip.
Figure 2
Figure 2
Histopathology of leukoplakia. (a) Hematoxylin and eosin staining (original magnification, ×100) showing keratin thickening with hyperkeratosis, intercellular edema, and prolonged protrusions in the epithelium. (b-d) Immunohistochemical staining; (b) Ki67, (c) p16, and (d) p53.
Figure 3
Figure 3
(a) Design of the resection with 5-mm margin. (b) The defect covering two-thirds of the lower lip. (c) The flap designed on the inferior surface of the tongue. (d) The flap harvested with a superior pedicle, 3-mm thick. (e) The flap applied over the defect. (f) The flap divided 2 weeks after the last operation.
Figure 4
Figure 4
The color and texture of the reconstructed lip (a) and the donor site (b) 6 months after the operation.
See this image and copyright information in PMC

References

    1. Warnakulasuriya S, Johnson NW, van der Waal I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med. 2007;36(10):575-580. doi:10.1111/j.1600-0714.2007.00582.x10.1111/j.1600-0714.2007.00582.x - DOI - DOI - PubMed
    1. Villa A, Sonis S. Oral leukoplakia remains a challenging condition. Oral Dis. 2018;24(1-2):179-183. doi:10.1111/odi.1278110.1111/odi.12781 - DOI - DOI - PubMed
    1. Kuribayashi Y, Tsushima F, Sato M, Morita K, Omura K. Recurrence patterns of oral leukoplakia after curative surgical resection: important factors that predict the risk of recurrence and malignancy. J Oral Pathol Med. 2012;41(9):682-688. doi:10.1111/j.1600-0714.2012.01167.x10.1111/j.1600-0714.2012.01167.x - DOI - DOI - PubMed
    1. de Azevedo AB, Dos Santos TCRB, Lopes MA, Pires FR. Oral leukoplakia, leukoerythroplakia, erythroplakia and actinic cheilitis: Analysis of 953 patients focusing on oral epithelial dysplasia. J Oral Pathol Med. 2021;50(8):829-840. doi:10.1111/jop.1318310.1111/jop.13183 - DOI - DOI - PubMed
    1. Sun K, Xia RH. Oral epithelial dysplasia and aphthous ulceration in a patient with ulcerative colitis: a case report. BMC Oral Health. 2023;23(1):143. Published 2023 Mar 11. doi:10.1186/s12903-023-02851-010.1186/s12903-023-02851-0 - DOI - DOI - PMC - PubMed

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