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Editorial

. 2024 Aug 27;332(8):623-625.

doi: 10.1001/jama.2024.10168.

Resolving the Dilemma on Continuous vs Intermittent β-Lactam Antibiotics in Sepsis

W Joost Wiersinga^{1

2

3}, Michiel A van Agtmael^{2

3

4}

Affiliations

Affiliations

¹ Center for Experimental and Molecular Medicine, Amsterdam University Medical Center, Amsterdam, the Netherlands.
² Department of Medicine, Division of Infectious Diseases, Amsterdam University Medical Center, Amsterdam, the Netherlands.
³ Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Center, Amsterdam, the Netherlands.
⁴ Department of Medicine, Section Pharmacotherapy, Amsterdam University Medical Center, Amsterdam, the Netherlands.

PMID: 38864160
DOI: 10.1001/jama.2024.10168

Editorial

Resolving the Dilemma on Continuous vs Intermittent β-Lactam Antibiotics in Sepsis

W Joost Wiersinga et al. JAMA. 2024.

. 2024 Aug 27;332(8):623-625.

doi: 10.1001/jama.2024.10168.

Authors

W Joost Wiersinga^{1

2

3}, Michiel A van Agtmael^{2

3

4}

Affiliations

¹ Center for Experimental and Molecular Medicine, Amsterdam University Medical Center, Amsterdam, the Netherlands.
² Department of Medicine, Division of Infectious Diseases, Amsterdam University Medical Center, Amsterdam, the Netherlands.
³ Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Center, Amsterdam, the Netherlands.
⁴ Department of Medicine, Section Pharmacotherapy, Amsterdam University Medical Center, Amsterdam, the Netherlands.

PMID: 38864160
DOI: 10.1001/jama.2024.10168

No abstract available

PubMed Disclaimer

Comment on

Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis: The BLING III Randomized Clinical Trial.
Dulhunty JM, Brett SJ, De Waele JJ, Rajbhandari D, Billot L, Cotta MO, Davis JS, Finfer S, Hammond NE, Knowles S, Liu X, McGuinness S, Mysore J, Paterson DL, Peake S, Rhodes A, Roberts JA, Roger C, Shirwadkar C, Starr T, Taylor C, Myburgh JA, Lipman J; BLING III Study Investigators. Dulhunty JM, et al. JAMA. 2024 Aug 27;332(8):629-637. doi: 10.1001/jama.2024.9779. JAMA. 2024. PMID: 38864155 Free PMC article. Clinical Trial.
Prolonged vs Intermittent Infusions of β-Lactam Antibiotics in Adults With Sepsis or Septic Shock: A Systematic Review and Meta-Analysis.
Abdul-Aziz MH, Hammond NE, Brett SJ, Cotta MO, De Waele JJ, Devaux A, Di Tanna GL, Dulhunty JM, Elkady H, Eriksson L, Hasan MS, Khan AB, Lipman J, Liu X, Monti G, Myburgh J, Novy E, Omar S, Rajbhandari D, Roger C, Sjövall F, Zaghi I, Zangrillo A, Delaney A, Roberts JA. Abdul-Aziz MH, et al. JAMA. 2024 Aug 27;332(8):638-648. doi: 10.1001/jama.2024.9803. JAMA. 2024. PMID: 38864162 Free PMC article.

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