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1 From the Center for Intelligent Imaging, Department of Radiology & Biomedical Imaging (B.K.K.F., E.C., J.M., S.C., C.P.H., L.P.S., T.L.L., J.E.V.M., A.M.R., J.D.R.), and Division of Neuro-Oncology, Department of Neurologic Surgery (S.M.C.), University of California San Francisco, 513 Parnassus Ave, Suite S-261D, Box 0628, San Francisco, CA 94143.
1 From the Center for Intelligent Imaging, Department of Radiology & Biomedical Imaging (B.K.K.F., E.C., J.M., S.C., C.P.H., L.P.S., T.L.L., J.E.V.M., A.M.R., J.D.R.), and Division of Neuro-Oncology, Department of Neurologic Surgery (S.M.C.), University of California San Francisco, 513 Parnassus Ave, Suite S-261D, Box 0628, San Francisco, CA 94143.
Disclosures of conflicts of interest: B.K.K.F. Received prior research grants from the RSNA R&E (2019-2020RMS #1909; 2018-2019 RMS #1810); consulting fees from Mendaera; honorarium payments from Neurodiem (invited author) and Elsevier (book proposal reviews); RSNA and institutional support for attending meetings (RSNA RFC stipend, institutional support stipend); vice-chair of the RSNA Resident and Fellow Committee; member of the American Board of Radiology Initial Certification Advisory Committee for Diagnostic Radiology, of the RSNA Education Council, and of the Radiology: Imaging Cancer Trainee Editorial Board; associate editor for Artificial Intelligence in Radiology with Frontiers in Radiology. E.C. Unrelated ASNR grant; unrelated Elsevier book royalties. J.M. Grant/contract from Siemens to institution; royalties from GE to author through institution; support for attending Nuance meetings; chair for RSNA’s Machine Learning Steering Committee; spouse employment at Annexon Biosciences; associate editor of Radiology: Artificial Intelligence. S.C. No relevant relationships. C.P.H. Consulting fees from GE HealthCare, Siemens Healthineers, and Kheiron Medical Technologies; participation on data safety monitoring board/advisory board for DSMB, Focused Ultrasound Foundation; DSMB, uniQure Biopharma; and DSMB, Asklepios BioPharma. L.P.S. No relevant relationships. S.M.C. AstraZeneca scientific advisory board. T.L.L. NICO Project, The Dabierre Family, Non-Invasive Characterization of Oligodrendroglioma. Coinvestigator; NIH P01CA118816 (PI Chang, Nelson, Vigneron) Noninvasive Metabolic Signatures to Improve Management of Molecular Subtypes of Glioma. Coinvestigator; Loglio Project. The Dabierre Family. Noninvasive Metabolic Signatures to Improve Management of Molecular Subtypes of Glioma. Coinvestigator; and DOD. (PI Li) Multimodal Neuroimaging for Evaluating Lower Grade Astrocytoma. Coinvestigator. All paid to institution. J.E.V.M. Grant/contract from GE HealthCare paid to UCSF. A.M.R. No relevant relationships. J.D.R. American Society of Neuroradiology Foundation Grant in Artificial Intelligence provided funding for this work, including salary/time and computing resources; consulting fees from Cortechs.ai; stock/stock options in Cortechs.ai and Subtle Medical.
Figures
Representative examples of brain MRI and tumor…
Representative examples of brain MRI and tumor segmentations in (A) a 55-year-old female patient with…
Representative examples of brain MRI and tumor segmentations in
(A) a 55-year-old female patient with glioblastoma and
(B) a 54-year-old female patient with glioblastoma.
Subtraction images show representative segmentations of longitudinal
(A) increases and (B) decreases in
surrounding nonenhancing fluid-attenuated inversion recovery (FLAIR)
hyperintensity (SNFH) and enhancing tissue (ET) in each patient,
respectively. T1ce = T1 contrast-enhanced, RC = resection cavity, NETC =
nonenhancing tumor core.
