Integrated functional analysis of endometrial transcriptome, microbiome, and immune cell profiling is needed to dissect mechanisms of uterine pathologies and implantation failure

Ganesh Acharya^{1

2}

Affiliations

¹ Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention & Technology (CLINTEC), Karolinska Institutet and Center for Fetal Medicine Karolinska, University Hospital, Stockholm, Sweden.
² Women's Health and Perinatology Research Group, Department of Clinical Medicine, UiT-The Arctic University of Norway, Tromsø, Norway.

Editorial

Ganesh Acharya. Acta Obstet Gynecol Scand. 2024 Jul.

. 2024 Jul;103(7):1236-1237.

doi: 10.1111/aogs.14882.

Ganesh Acharya^{1

2}

¹ Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention & Technology (CLINTEC), Karolinska Institutet and Center for Fetal Medicine Karolinska, University Hospital, Stockholm, Sweden.
² Women's Health and Perinatology Research Group, Department of Clinical Medicine, UiT-The Arctic University of Norway, Tromsø, Norway.

No abstract available

References

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1. Wang W, Vilella F, Alama P, et al. Single‐cell transcriptomic atlas of the human endometrium during the menstrual cycle. Nat Med. 2020;26:1644‐1653. - PubMed
1. Walker ER, McGrane M, Aplin JD, Brison DR, Ruane PT. A systematic review of transcriptomic studies of the human endometrium reveals inconsistently reported differentially expressed genes. Reprod Fertil. 2023;4:e220115. - PMC - PubMed
1. Inversetti A, Zambella E, Guarano A, Dell'Avanzo M, Di Simone N. Endometrial microbiota and immune tolerance in pregnancy. Int J Mol Sci. 2023;24:2995. - PMC - PubMed