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. 2024 Jun 7:66:e37.
doi: 10.1590/S1678-9946202466037. eCollection 2024.

Impact of COVID-19 on tuberculosis notifications

Talita Antunes Antoniolli Pontes  1 , Fernando Fernandez-Llimos  2 , Astrid Wiens  3
Affiliations

Impact of COVID-19 on tuberculosis notifications

Talita Antunes Antoniolli Pontes et al. Rev Inst Med Trop Sao Paulo. .

Abstract

The COVID-19 pandemic has significantly impacted the control of diseases by overwhelming healthcare systems, and tuberculosis (TB) notifications may have been affected. This study aimed to analyze the impact of COVID-19 on TB notifications in the Sao Paulo State. This is a retrospective study examining TB notifications extracted from the TBweb database (Jan 2015 to Dec 2022). We conducted an interrupted time series (ITS) analysis of TB notifications using the declaration of the COVID-19 pandemic as the interrupting event (Bayesian causal impact analysis). A total of 177,103 notifications of TB incident cases were analyzed, revealing a significant decrease in 2020 (13%) and in 2021 (9%), which lost significance in 2022. However, changes were not associated with population density or the area of the regions. Future analyses of the effects of TB underdiagnosis might help describe the impact of underreporting on future TB incidence and mortality.

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Conflict of interest statement

CONFLICT OF INTERESTS

The authors have no conflict of interests to declare.

Figures

Figure 1
Figure 1. Incidence of tuberculosis in Sao Paulo State municipalities (excluding imprisoned population).
Figure 2
Figure 2. Interrupted time series analysis of tuberculosis notifications from 2015 to 2022.
Figure 3
Figure 3. Impact of COVID-19 on tuberculosis incidence in Sao Paulo State at the immediate region level.
See this image and copyright information in PMC

References

    1. World Health Organization . Global tuberculosis report 2021. Geneva: WHO; 2021. [[cited 2024 Apr 15]]. Available from: https://www.who.int/publications/i/item/9789240037021 .
    1. Portugal. Direção-Geral da Saúde . Despacho n.º 1150/2021, de 28 de janeiro - Doenças de notificação obrigatória a notificar na plataforma de apoio ao SINAVE (Sistema Nacional de Vigilância Epidemiológica) ou no SI-Vida (Sistema de informação VIH/SIDA) Vol. 19. Diário da República; Lisboa: Jan 28, 2021. [[cited 2024 Apr 15]]. Série II:137-90. Available from https://diariodarepublica.pt/dr/detalhe/despacho/1150-2021-155575942 .
    1. World Health Organization . WHO global lists of high burden countries for TB, multidrug/rifampicin-resistant TB (MDR/RR-TB) and TB/HIV, 2021-2025. Geneva: WHO; 2021. [[cited 2024 Apr 15]]. Available from https://cdn.who.int/media/docs/default-source/hq-tuberculosis/who_global... .
    1. Jeong Y, Min J. Impact of COVID-19 pandemic on tuberculosis preventive services and their post-pandemic recovery strategies: a rapid review of literature. J Korean Med Sci. 2023;38:e43. - PMC - PubMed
    1. Brasil. Ministério da Saúde Plataforma Integrada de Vigilância em Saúde. Doença pelo Coronavírus 2019 (Covid-19) [[cited 2024 Apr 15]]. Available from http://plataforma.saude.gov.br/coronavirus/