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Comment
. 2024 Jun 11;57(6):1182-1184.
doi: 10.1016/j.immuni.2024.05.011.

Mast cells: The Janus of type 2 inflammation

Johanna Kotrba  1 , Anne Dudeck  2
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Free article
Comment

Mast cells: The Janus of type 2 inflammation

Johanna Kotrba et al. Immunity. .
Free article

Abstract

Mast cells (MCs) are effectors in type 2 immunity, well known for their detrimental roles in allergy. In this issue of Immunity, Alhallak et al. now identify a protective role of MCs against exacerbated immune responses mediated by prostaglandin E2 (PGE2)-driven soluble ST2.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

  • Mast cells control lung type 2 inflammation via prostaglandin E2-driven soluble ST2.
    Alhallak K, Nagai J, Zaleski K, Marshall S, Salloum T, Derakhshan T, Hayashi H, Feng C, Kratchmarov R, Lai J, Kuchibhotla V, Nishida A, Balestrieri B, Laidlaw T, Dwyer DF, Boyce JA. Alhallak K, et al. Immunity. 2024 Jun 11;57(6):1274-1288.e6. doi: 10.1016/j.immuni.2024.05.003. Epub 2024 May 30. Immunity. 2024. PMID: 38821053 Free PMC article.

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