Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Sep;22(3):311-321.
doi: 10.1111/vco.12980. Epub 2024 Jun 12.

Electrochemotherapy in dogs and cats-A review

Sofia Chichorro Ramos  1 , Patrícia Dias-Pereira  2 , Ana Lúcia Luís  2 , Michael MacFarlane  1 , Andreia Alexandra Santos  2
Affiliations
Review

Electrochemotherapy in dogs and cats-A review

Sofia Chichorro Ramos et al. Vet Comp Oncol. 2024 Sep.

Abstract

Electrochemotherapy (ECT) is a treatment modality that combines the electroporation of cell membranes with chemotherapy to facilitate the transport of non-permeant molecules into cells. Several canine and feline studies have shown promising results, suggesting that ECT can be a valid adjuvant or alternative treatment option for some tumours. The objective of this paper is to provide a bibliographic review of the principles and applications of ECT in veterinary medicine and to compare to its use in human medicine.

Keywords: electrochemotherapy; electroporation; small animals; tumours.

PubMed Disclaimer

References

REFERENCES

    1. Mir LM , Belehradek M , Domenge C , et al. Electrochemotherapy, a new antitumour treatment: first clinical trial. C R Acad Sci. 1991;3(313):613‐618.
    1. Mir LM , Gehl J , Sersa G , et al. Standard operating procedures of the electrochemotherapy: instructions for the use of bleomycin or cisplatin administered either systemically or locally and electric pulses delivered by the CliniporatorTM by means of invasive or non‐invasive electrodes. Eur J Cancer Suppl. 2006;4:14‐25.
    1. Mir LM , Devauchelle P , Quintin‐Colonna F , et al. First clinical trial of cat soft‐tissue sarcomas treatment by electrochemotherapy. Br J Cancer. 1997;76:1617‐1622.
    1. Spugnini EP , Azzarito T , Fais S , Fanciulli M , Baldi A . Electrochemotherapy as first line cancer treatment: experiences from veterinary medicine in developing novel protocols. Curr Cancer Drug Targets. 2016;16:43‐52.
    1. Spugnini EP , Fanciulli M , Citro G , Baldi A . Preclinical models in electrochemotherapy: the role of veterinary patients. Future Oncol. 2012;8:829‐837.

Substances

LinkOut - more resources