doi: 10.1083/jcb.100.5.1637.
Active maturation-promoting factor is present in mature mouse oocytes
- PMID: 3886670
- PMCID: PMC2113872
- DOI: 10.1083/jcb.100.5.1637
Item in Clipboard
Active maturation-promoting factor is present in mature mouse oocytes
J Cell Biol.
1985 May.
Abstract
Cytoplasmic extracts of meiotically mature mouse oocytes were injected into immature Xenopus laevis oocytes, which underwent germinal vesicle breakdown within 2 h. Germinal vesicle breakdown was not inhibited by incubation of the Xenopus oocytes in cycloheximide (20 micrograms/ml). Identically prepared extracts of meiotically immature mouse oocytes, arrested at the germinal vesicle stage by dibutyryl cyclic AMP (100 micrograms/ml), did not induce germinal vesicle breakdown in Xenopus oocytes. The results show that maturation-promoting factor activity appears during the course of oocyte maturation in the mouse.
Similar articles
-
Cell cycle dynamics of an M-phase-specific cytoplasmic factor in Xenopus laevis oocytes and eggs.J Cell Biol. 1984 Apr;98(4):1247-55. doi: 10.1083/jcb.98.4.1247. J Cell Biol. 1984. PMID: 6425302 Free PMC article.
-
Cell cycle dynamics of maturation-promoting factor during mouse oocyte maturation.Tokai J Exp Clin Med. 1986 Dec;11(6):471-7. Tokai J Exp Clin Med. 1986. PMID: 2832978
-
Induction of maturation in small Xenopus laevis oocytes.Dev Biol. 1987 May;121(1):111-8. doi: 10.1016/0012-1606(87)90144-8. Dev Biol. 1987. PMID: 3552785
-
Regulation of oocyte maturation.Curr Top Cell Regul. 1980;16:271-311. doi: 10.1016/b978-0-12-152816-4.50012-1. Curr Top Cell Regul. 1980. PMID: 6249544 Review. No abstract available.
-
Maturation and fertilization in starfish oocytes.Int Rev Cytol. 1984;86:129-96. doi: 10.1016/s0074-7696(08)60179-5. Int Rev Cytol. 1984. PMID: 6423562 Review. No abstract available.
Cited by
-
Transformation of sperm nuclei to metaphase chromosomes in the cytoplasm of maturing oocytes of the mouse.J Cell Biol. 1986 Mar;102(3):1039-46. doi: 10.1083/jcb.102.3.1039. J Cell Biol. 1986. PMID: 3949872 Free PMC article.
-
Demonstration of maturation-promoting and -inhibiting activities in mouse oocytes.J In Vitro Fert Embryo Transf. 1990 Oct;7(5):271-4. doi: 10.1007/BF01129533. J In Vitro Fert Embryo Transf. 1990. PMID: 1701472
-
Metaphase protein phosphorylation in Xenopus laevis eggs.Mol Cell Biol. 1987 Feb;7(2):760-8. doi: 10.1128/mcb.7.2.760-768.1987. Mol Cell Biol. 1987. PMID: 3821728 Free PMC article.
-
cdc2 and the regulation of mitosis: six interacting mcs genes.Genetics. 1989 Aug;122(4):773-82. doi: 10.1093/genetics/122.4.773. Genetics. 1989. PMID: 2474475 Free PMC article.
-
Study of the in vitro maturation of mouse oocytes induced by microinjection of maturation promoting factor (MPF).J Assist Reprod Genet. 2000 Jan;17(1):67-73. doi: 10.1023/a:1009458215882. J Assist Reprod Genet. 2000. PMID: 10754786 Free PMC article.
