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Review
. 2024 Jun 13;18(1):277.
doi: 10.1186/s13256-024-04474-7.

Giant complete hydatidiform mole: a case report and review of the literature

Iris Bonomo  1 , Suzy Fopa  2 , Grégory Van Vinckenroy  3 , Charlotte Maillard  4
Affiliations
Review

Giant complete hydatidiform mole: a case report and review of the literature

Iris Bonomo et al. J Med Case Rep. .

Abstract

Background: This case describes the youngest patient documented in the literature who presented with a giant hydatidiform mole, effectively addressed through conservative treatment.

Case presentation: Our department received a 20-year-old Caucasian patient who was admitted due to significant metrorrhagia in an undisclosed pregnancy. During examination, we identified a massive, highly vascularized hydatidiform mole measuring 22 cm (cm). We performed a surgical dilatation and curettage. The anatomopathological findings confirmed the presence of a complete hydatidiform mole (CHM). Following the established guidelines, we conducted weekly monitoring of human chorionic gonadotropin (hCG). Unfortunately, the patient discontinued the follow-up and became pregnant again before achieving hCG negativation.

Conclusion: This case suggests that conservative treatment is a viable option regardless of the size of gestational trophoblastic disease (GTD), especially when the preservation of fertility is a crucial consideration, as effectively demonstrated in our case.

Keywords: Case report; Gestational trophoblastic disease; Human chorionic gonadotropin; Hydatidiform mole; Molar pregnancy.

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Conflict of interest statement

The authors have no conflict of interest.

Figures

Fig. 1
Fig. 1
Preoperative thoracoabdominal CT scan
Fig. 2
Fig. 2
Dilatation and curettage under ultrasound guidance
Fig. 3
Fig. 3
Uterine contents after curettage
See this image and copyright information in PMC

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