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. 2024 May 6;3(2):e195.
doi: 10.1002/pcn5.195. eCollection 2024 Jun.

Association of schizophrenia with fracture-related femoral neck displacement: A cross-sectional retrospective study

Yukiyo Inoue  1   2 , Akihiro Tokushige  3 , Takeshi Kinjyo  4 , Shinichiro Ueda  2   3
Affiliations

Association of schizophrenia with fracture-related femoral neck displacement: A cross-sectional retrospective study

Yukiyo Inoue et al. PCN Rep. .

Abstract

Aim: Fracture-related femoral neck displacement is more likely in patients with schizophrenia because of delayed diagnosis, as these patients frequently have less severe fracture-associated subjective symptoms. This study aimed to investigate the association of schizophrenia with the risk of fracture-related femoral neck displacement in hospitalized patients.

Methods: We retrospectively analyzed the medical records of patients with femoral neck fractures treated between April 2013 and March 2018 at a single institution. Multivariate logistic regression was used to explore the relationship between schizophrenia and fracture-related femoral neck displacement after adjusting for risk factors.

Results: We compared 30 and 194 patients with and without schizophrenia, respectively. The prevalence of fracture-related displacement was 80.0% in patients with schizophrenia and 62.4% in the controls (p = 0.06). After adjusting for confounding variables, schizophrenia significantly correlated with fracture-related femoral neck displacement (odds ratio: 4.74, 95% confidence interval: 1.09-20.60, p = 0.0378).

Conclusions: Schizophrenia is associated with a higher risk of severe femoral neck fracture. To improve outcomes and alleviate the societal burden of femoral neck fractures, early radiographic assessment and surgical intervention for femoral fractures are essential for patients with schizophrenia, even in those without pain symptoms.

Keywords: displacement; femoral neck fracture; garden classification; schizophrenia.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Flowchart of the participant selection and enrolment in the study.
See this image and copyright information in PMC

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