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Observational Study
. 2024 Nov;34(11):4152-4165.
doi: 10.1007/s11695-024-07296-0. Epub 2024 Jun 13.

Global 30-Day Morbidity and Mortality of Primary Bariatric Surgery Combined with Another Procedure: The BLEND Study

Alessandro Martinino  1 Kushan D L Nanayakkara  2 Brij Madhok  2 Geoffrey Yuet Mun Wong  3 Mohamed Abouelazayem  4 Juan Pablo Scarano Pereira  5 Ishaan Wazir  6 Vignesh Balasubaramaniam  7 Amira Said  8 Cláudia Marques  9 Amr Abdelbaeth  10 Khayry Al-Shami  11 Muna Albashari  12 Akram Alkaseek  13 Mohammad Abdullah Almayouf  14 Mohammad Aloulou  15 Awadh Robaan Alqahtan  16 Alan Askari  17 Meena Faiez Assad Attia  18 Ahmed K Awad  18 Muhammed Rasid Aykota  19 Nicolae Bacalbasa  20 Francisco J Barrera-Rodriguez  21 Domenico Benavoli  22 Srikar Billa  23 Vincenzo Borrelli  24 İsmail Çalıkoğlu  25 Michela Campanelli  22 Miguel A Carbajo  26 Sharfuddin Chowdhury  27 Luca Cristin  28 Giovanni Dapri  29 Zhiyong Dong  30 Mohamad Hayssam Elfawal  31 Amr Elgazar  18 Muhammed Elhadi  32 Paolo Gentileschi  22 Yitka Graham  33 Bassel Haj  34   35 Joseph Andrew Johnson  36 Abd-Elfattah Morsi Kalmoush  37 Ayman Kamal  10 Anna Kamocka  36 Almu'atasim Khamees  11 Giorgio Lisi  38 Edgard Efren Lozada Hernandez  39 Giuseppe M Marinari  24 Gennaro Martines  40 Serhat Meric  41 Fernando Mier  42 Ahmed Mohamed Ali  10 Diyaaldeen Mohammed  31 Karim Mostafa Mohamed  10 Francesk Mulita  43 Mario Musella  44 William Edward O'Malley  36 Stefano Olmi  45 Taryel Omarov  46 Omnya Osama  10 HMinali R Perera  17 Giovanni Piscitelli  24 Tigran Poghosyan  47 David Ramírez  26 Masoud Rezvani  48 Rui Ribeiro  49 Aaron Sabbota  36 Nasser Sakran  34   36 Khaled Ahmad Sawaftah  11 Kaci Schiavone  36 Ozan Şen  50 Maria Sotiropoulou  51 Nicola Tartaglia  52 Merve Tokocin  41 Manuela Trotta  24 Ahmet Gökhan Türkçapar  53 Matteo Uccelli  45 Cesar Vargas  54 Georgios -Ioannis Verras  43 Cunchuan Wang  30 Zhuoqi Wei  30 Wah Yang  30 Carlos Zerrweck  54 Eloise Owen  55 Georgios V Gkoutos  56 Victor Roth Cardoso  56 Rishi Singhal  57 Kamal Mahawar  58 BLEND Study Collaborative Group
Collaborators, Affiliations
Observational Study

Global 30-Day Morbidity and Mortality of Primary Bariatric Surgery Combined with Another Procedure: The BLEND Study

Alessandro Martinino et al. Obes Surg. 2024 Nov.

Abstract

Background: No robust data are available on the safety of primary bariatric and metabolic surgery (BMS) alone compared to primary BMS combined with other procedures.

Objectives: The objective of this study is to collect a 30-day mortality and morbidity of primary BMS combined with cholecystectomy, ventral hernia repair, or hiatal hernia repair.

Setting: This is as an international, multicenter, prospective, and observational audit of patients undergoing primary BMS combined with one or more additional procedures.

Methods: The audit took place from January 1 to June 30, 2022. A descriptive analysis was conducted. A propensity score matching analysis compared the BLEND study patients with those from the GENEVA cohort to obtain objective evaluation between combined procedures and primary BMS alone.

Results: A total of 75 centers submitted data on 1036 patients. Sleeve gastrectomy was the most commonly primary BMS (N = 653, 63%), and hiatal hernia repair was the most commonly concomitant procedure (N = 447, 43.1%). RYGB accounted for the highest percentage (20.6%) of a 30-day morbidity, followed by SG (10.5%). More than one combined procedures had the highest morbidities among all combinations (17.1%). Out of overall 134 complications, 129 (96.2%) were Clavien-Dindo I-III, and 4 were CD V. Patients who underwent a primary bariatric surgery combined with another procedure had a pronounced increase in a 30-day complication rate compared with patients who underwent only BMS (12.7% vs. 7.1%).

Conclusion: Combining BMS with another procedure increases the risk of complications, but most are minor and require no further treatment. Combined procedures with primary BMS is a viable option to consider in selected patients following multi-disciplinary discussion.

Keywords: Combined procedures; Concomitant cholecystectomy; Concomitant hiatal hernia repair; Concomitant ventral hernia repair; Primary bariatric and metabolic surgery.

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