Treatment strategies and biomarkers in Crohn's disease: the PROFILE trial

doi:10.1016/S2468-1253(24)00082-7

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. 2024 Jul;9(7):591-592.

doi: 10.1016/S2468-1253(24)00082-7.

Treatment strategies and biomarkers in Crohn's disease: the PROFILE trial

Jack Satsangi¹, Jan Nowak², Rahul Kalla³, Jean-Frederic Colombel⁴

Affiliations

¹ Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford OX3 9DU, UK. Electronic address: jack.satsangi@ndm.ox.ac.uk.
² Poznan University of Medical Sciences, Poznan, Poland.
³ Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK.
⁴ Icahn School of Medicine at Mount Sinai, New York, NY, USA.

PMID: 38870964
DOI: 10.1016/S2468-1253(24)00082-7

Comment

Treatment strategies and biomarkers in Crohn's disease: the PROFILE trial

Jack Satsangi et al. Lancet Gastroenterol Hepatol. 2024 Jul.

. 2024 Jul;9(7):591-592.

doi: 10.1016/S2468-1253(24)00082-7.

Authors

Jack Satsangi¹, Jan Nowak², Rahul Kalla³, Jean-Frederic Colombel⁴

Affiliations

¹ Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford OX3 9DU, UK. Electronic address: jack.satsangi@ndm.ox.ac.uk.
² Poznan University of Medical Sciences, Poznan, Poland.
³ Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK.
⁴ Icahn School of Medicine at Mount Sinai, New York, NY, USA.

PMID: 38870964
DOI: 10.1016/S2468-1253(24)00082-7

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Treatment strategies and biomarkers in Crohn's disease: the PROFILE trial - Authors' reply.
Noor NM, Lee JC, Bond S, Parkes M. Noor NM, et al. Lancet Gastroenterol Hepatol. 2024 Jul;9(7):592-594. doi: 10.1016/S2468-1253(24)00150-X. Lancet Gastroenterol Hepatol. 2024. PMID: 38870966 No abstract available.

Comment on

A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE): a multicentre, open-label randomised controlled trial.
Noor NM, Lee JC, Bond S, Dowling F, Brezina B, Patel KV, Ahmad T, Banim PJ, Berrill JW, Cooney R, De La Revilla Negro J, de Silva S, Din S, Durai D, Gordon JN, Irving PM, Johnson M, Kent AJ, Kok KB, Moran GW, Mowat C, Patel P, Probert CS, Raine T, Saich R, Seward A, Sharpstone D, Smith MA, Subramanian S, Upponi SS, Wiles A, Williams HRT, van den Brink GR, Vermeire S, Jairath V, D'Haens GR, McKinney EF, Lyons PA, Lindsay JO, Kennedy NA, Smith KGC, Parkes M; PROFILE Study Group. Noor NM, et al. Lancet Gastroenterol Hepatol. 2024 May;9(5):415-427. doi: 10.1016/S2468-1253(24)00034-7. Epub 2024 Feb 22. Lancet Gastroenterol Hepatol. 2024. PMID: 38402895 Free PMC article. Clinical Trial.

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Treatment strategies and biomarkers in Crohn's disease: the PROFILE trial

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Treatment strategies and biomarkers in Crohn's disease: the PROFILE trial

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