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Review
. 2024 Jun 12;23(1):e0187.
doi: 10.1097/CLD.0000000000000187. eCollection 2024 Jan-Jun.

Managing pruritus in chronic liver disease: An in-depth narrative review

Ana Marenco-Flores  1 , Leandro Sierra  1 , Daniela Goyes  2 , Tamara Kahan  3 , Vilas R Patwardhan  1 , Alan Bonder  1
Affiliations
Review

Managing pruritus in chronic liver disease: An in-depth narrative review

Ana Marenco-Flores et al. Clin Liver Dis (Hoboken). .
No abstract available

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Conflict of interest statement

Alan Bonder consults for and received grants from GSK, Intercept, Mirum, and Ipsen. He consults for Zydus, ChemomAb, CymbaBay, Gilead and CARA. He received royalties or holds licenses from UpToDate and DynaMed. He has given expert testimony for Expert Review, Inc. He has other interests with Pfizer. The remaining authors have no conflicts to report.

Figures

None
Graphical abstract
FIGURE 1
FIGURE 1
Assessment of the severity of pruritus. Visual Analog Scale: 0% = no pruritus; 10%–30% = mild pruritus; 40%–60% = moderate pruritus; 70%–80% = severe pruritus; 90%–100% = very severe pruritus. 5D Itch Scale: The domain scores are added together, potentially ranging from 5 (no pruritus) to 25 (most severe pruritus). PBC-40: Items are scored from 1 to 5 (never, rarely, sometimes, most of the time, and always), and the individual item scores are summed to give a total domain. Abbreviation: PBC, primary biliary cholangitis.
FIGURE 2
FIGURE 2
Current therapeutic recommendation for the management of pruritus in cholestatic liver diseases. Abbreviations: ICP, intrahepatic cholestasis of pregnancy; mg, milligrams; PXR, pregnane X receptor.
See this image and copyright information in PMC

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References

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