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. 2024 Jun 15;28(7):375.
doi: 10.1007/s00784-024-05784-2.

Effect of mineralized dentin matrix on the prognosis of bone defect and retained root after coronectomy

Bin-Zhang Wu #  1 , Jing-Yu Zhang #  2 , Jin-Yang Xu #  2 , Fei Wang #  3 , Zi-Yu Yan  4 , Nian-Hui Cui  5
Affiliations

Effect of mineralized dentin matrix on the prognosis of bone defect and retained root after coronectomy

Bin-Zhang Wu et al. Clin Oral Investig. .

Abstract

Objective: To investigate the impact of mineralized dentin matrix (MDM) on the prognosis on bone regeneration and migration of retained roots after coronectomy.

Materials and methods: Patients were divided into three groups based on the type of bone graft after coronectomy: Group C (n = 20, collagen), Group T (n = 20, tricalcium phosphate (TCP) + collagen), and Group D (n = 20, MDM + collagen). CBCT scans, conducted immediately and 6 months after surgery, were analyzed using digital software. Primary outcomes, including changes in bone defect depth and retained root migration distance, were evaluated 6 months after surgery.

Results: After 6 months, both Groups D and T exhibited greater reduction of the bone defect and lesser retained root migration than Group C (p < 0.001). Group D had greater regenerated bone volume in the distal 2 mm (73 mm3 vs. 57 mm3, p = 0.011) and lesser root migration (2.18 mm vs. 2.96 mm, p < 0.001) than Group T. The proportion of completely bone embedded retained roots was also greater in Group D than in Group C (70.0% vs. 42.1%, p = 0.003).

Conclusions: MDM is an appropriate graft material for improving bone defect healing and reducing retained root migration after coronectomy.

Clinical relevance: MDM is an autogenous material prepared chairside, which can significantly improve bone healing and reduce the risk of retained root re-eruption. MDM holds promise as a routine bone substitute material after M3M coronectomy.

Keywords: Bone regeneration; Bone substitutes; Coronectomy; Dentin; Digital technologies.

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