Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1985 Mar;27(3):309-13.
doi: 10.1128/AAC.27.3.309.

Ribavirin small-particle aerosol treatment of infections caused by influenza virus strains A/Victoria/7/83 (H1N1) and B/Texas/1/84

B E Gilbert, S Z Wilson, V Knight, R B Couch, J M Quarles, L Dure, N Hayes, G Willis
Clinical Trial

Ribavirin small-particle aerosol treatment of infections caused by influenza virus strains A/Victoria/7/83 (H1N1) and B/Texas/1/84

B E Gilbert et al. Antimicrob Agents Chemother. 1985 Mar.

Abstract

In a double-blind study of influenza in a population of college students in 1984, ribavirin small-particle aerosol treatment of 38 patients (18 treated, 20 control) infected with a new antigenic variant, influenza virus strain A/Victoria/7/83 (H1N1), was associated with statistically significant reductions in the height and duration of fever, systemic symptoms, and virus shedding. Patients received a total of 2.4 g of ribavirin over 42 h during 68 h of hospitalization without any side effects. In addition, in a study of patients infected with influenza virus strain B/Texas/1/84 (seven treated, eight control) treated with ribavirin aerosol showed a trend of more rapid recovery than control patients.

PubMed Disclaimer

References

    1. JAMA. 1983 May 20;249(19):2671-4 - PubMed
    1. N Engl J Med. 1983 Jun 16;308(24):1443-7 - PubMed
    1. Antimicrob Agents Chemother. 1984 Aug;26(2):200-3 - PubMed
    1. Lancet. 1981 Oct 31;2(8253):945-9 - PubMed
    1. J Clin Microbiol. 1979 Jul;10(1):32-6 - PubMed

Publication types