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Review
. 2024 Oct;21(10):e202400808.
doi: 10.1002/cbdv.202400808. Epub 2024 Sep 12.

Abietane-Type Diterpenoids: Insights into Structural Diversity and Therapeutic Potential

Zahra Sargazifar  1 , Danial Ghorbanian Charami  2 , Marziyeh Esmaeilzadeh Kashi  2 , Javad Asili  2 , Abolfazl Shakeri  2
Affiliations
Review

Abietane-Type Diterpenoids: Insights into Structural Diversity and Therapeutic Potential

Zahra Sargazifar et al. Chem Biodivers. 2024 Oct.

Abstract

The abietane-type diterpenoids are among the most significant diterpene subsets found in hundreds of plant species belonging to various families. Among which, the members of the genus Salvia and Euphorbia are rich in abietane diterpenoids. Because of the chemical diversity and notable bioactivities, such as anticancer, antiinflammatory, antimicrobial, and antioxidant activities, they are attractive. Herein, recent advances in the isolation and characterization of abietanes from natural sources, as well as their biological activities, from 2015 up to 2024 are reviewed. During this time, over 300 abietanes with diverse structures have been discovered.

Keywords: Abietane; Biological activities; Diterpenoids; Lamiaceae.

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