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Review
. 2024 May 29;9(23):24219-24235.
doi: 10.1021/acsomega.4c02847. eCollection 2024 Jun 11.

Recent Advances in the Application of 3D-Printing Bioinks Based on Decellularized Extracellular Matrix in Tissue Engineering

Haoxin Wan  1 , Jian Xiang  2 , Guocai Mao  1 , Shu Pan  1 , Bing Li  3 , Yi Lu  4
Affiliations
Review

Recent Advances in the Application of 3D-Printing Bioinks Based on Decellularized Extracellular Matrix in Tissue Engineering

Haoxin Wan et al. ACS Omega. .

Abstract

In recent years, 3D bioprinting with various types of bioinks has been widely used in tissue engineering to fabricate human tissues and organs with appropriate biological functions. Decellularized extracellular matrix (dECM) is an excellent bioink candidate because it is enriched with a variety of bioactive proteins and bioactive factors and can provide a suitable environment for tissue repair or tissue regeneration while reducing the likelihood of severe immune rejection. In this Review, we systematically review recent advances in 3D bioprinting and decellularization technologies and comprehensively detail the latest research and applications of dECM as a bioink for tissue engineering in various systems, with the aim of providing a reference for researchers in tissue engineering to better understand the properties of dECM bioinks.

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Conflict of interest statement

The authors declare no competing financial interest.

Figures

Figure 1
Figure 1
3D-printing bioinks based on decellularized extracellular matrix in tissue engineering.
Figure 2
Figure 2
Number of publications from 2015−2024.
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Figure 3
Number of publications by country and country cooperation network diagram
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Figure 4
Author collaboration diagram.
Figure 5
Figure 5
Statistics of published articles in the institutions.
Figure 6
Figure 6
Keyword occurrence analysis.
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