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Case Reports
. 2024 Apr;16(Suppl 2):S1888-S1891.
doi: 10.4103/jpbs.jpbs_1210_23. Epub 2024 Apr 16.

2-Staged Surgical Protocol for Management of Large Odontogenic Keratocyst

Prachur Malhotra  1 , Debasish Sinha  1 , Saurabh Chandalia  1 , Deep Shah  1 , Mrudula Mulay  1 , Kreena Shah  1
Affiliations
Case Reports

2-Staged Surgical Protocol for Management of Large Odontogenic Keratocyst

Prachur Malhotra et al. J Pharm Bioallied Sci. 2024 Apr.

Abstract

The World Health Organisation classification and the treatment protocol for the odontogenic keratocyst (OKC), previously referred to as the keratocystic odontogenic tumour, were examined based on a study of the literature. Because not all OKCs have an identifiable protein patched homolog mutation, the idea of changing the management protocol for OKC in response to this shift in tumour category was met with scepticism and was not widely adopted. This study's objective was to outline a successful management plan for an odontogenic keratocyst in a patient who was 23 years old. The procedure for therapy involved marsupialisation, which was followed by enucleation, peripheral osteotomy, and the injection of 5 FFU. Following a 2-year observation period (clinical and radiological monitoring), it was found that bone regeneration was normal and there was no sign of a recurrence.

Keywords: Enucleation; marsupialisation; odontogenic keratocyst; recurrence.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Pre-operative photograph
Figure 2
Figure 2
Pre-operative radiograph
Figure 3
Figure 3
Acrylic plate with acrylic plug
Figure 4
Figure 4
Post-marsupialisation cavity and acrylic plate with plug
Figure 5
Figure 5
Post-marsupialisation 6 months follow-up radiograph
Figure 6
Figure 6
Pre-enucleation photographs
Figure 7
Figure 7
Pre-enucleation radiograph
Figure 8
Figure 8
Enucleation photographs
Figure 9
Figure 9
Post-operative photographs
Figure 10
Figure 10
Post-operative radiograph
Figure 11
Figure 11
Post-enucleation 26 months follow-up radiograph
See this image and copyright information in PMC

References

    1. Kaczmarzyk T, Stypułkowska J, Tomaszewska R. Update of the WHO classification of odontogenic and maxillofacial bone tumors. J Stomatol. 2017;70:484–506.
    1. Soluk-Tekkeşin M, Wright JM. The World Health Organization classification of odontogenic lesions: A summary of the changes of the 2017 (4th) edition. Turk Patoloji Derg. 2018;34:1–18. - PubMed
    1. El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ, editors. WHO Classification of Head and Neck Tumours. Lyon, France: IARC (WHO); 2017. pp. 235–6.
    1. Robinson RA, Vincent SD. Tumors and Cysts of the Jaws (AFIP Atlas of Tumor Pathology, Series 4, Number 16) Silver Spring, MD: ARP. 2012:30–2.
    1. Sapp JP, Eversole LR, Wysocki GP. Contemporary Oral and Maxillofacial Pathology. 2nd ed. St. Louis, MO: Mosby; 2004. pp. 54–6.

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