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Case Reports
. 2024 Apr 26:49:62-64.
doi: 10.1016/j.jdcr.2024.03.024. eCollection 2024 Jul.

Unilateral demodicidosis of the nipple/areola complex mimicking nevoid hyperkeratosis

Valentina Caputo  1 , Donata Calò  2 , Franco Rongioletti  3
Affiliations
Case Reports

Unilateral demodicidosis of the nipple/areola complex mimicking nevoid hyperkeratosis

Valentina Caputo et al. JAAD Case Rep. .
No abstract available

Keywords: demodicidosis; demodicosis; nevoid hyperkeratosis; nipple.

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Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
Brownish verrucous plaques on left areola, slightly involving also the nipple for 2 months. Some scattered white filiform protrusions are visible.
Fig 2
Fig 2
Skin scraping revealed Demodex folliculorum mites.
Fig 3
Fig 3
Histopathology showed flat epidermis with overlying thick hyperkeratosis dilated infundibulum with many Demodex folliculorum mites and a perivascular and perifollicular lymphocytic infiltrate with some neutrophils in the superficial dermis.
Fig 4
Fig 4
Topical treatment with 1% ivermectin cream twice a day with 10% urea led to complete clearing of skin lesions after 4 weeks.
See this image and copyright information in PMC

References

    1. Chen W., Plewig G. Human demodicosis: revisit and a proposed classification. Br J Dermatol. 2014;170:1219–1225. doi: 10.1111/bjd.12850. - DOI - PubMed
    1. Feuerman H., Atzmony L., Glick M., et al. Pigmented demodicidosis - an under-recognized cause of facial hyperpigmentation. Int J Dermatol. 2022;61:564–569. doi: 10.1111/ijd.15992. - DOI - PubMed
    1. Garven H.S. Demodex folliculorum in the human nipple. Lancet. 1946;2:44–46. - PubMed
    1. Val-Bernal J.F., Diego C., Rodriguez-Villar D., Garijo M.F. The nipple-areola complex epidermis: a prospective systematic study in adult autopsies. Am J Dermatopathol. 2010;32:787–793. - PubMed
    1. Fidler W.J. Demodex folliculorum in a nipple imprint. Acta Cytol. 1978;22:168–169. - PubMed

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