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Case Reports
. 2024 May 9:49:68-70.
doi: 10.1016/j.jdcr.2024.04.038. eCollection 2024 Jul.

A case of Darier disease with perioral cutaneous cobblestoning treated with dupilumab

Sara Holt  1 , Sherlyn Saju  1 , Richard Miller  1
Affiliations
Case Reports

A case of Darier disease with perioral cutaneous cobblestoning treated with dupilumab

Sara Holt et al. JAAD Case Rep. .
No abstract available

Keywords: Darier disease; cutaneous cobblestoning; dupilumab; genodermatoses.

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Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
Darier disease. Pink to flesh colored pinpoint smooth papules forming a cobblestoned plaque with fissuring and crusting, concentrated in a perioral distribution in a patient with severe Darier disease.
Fig 2
Fig 2
Darier disease. Hematoxylin and eosin staining of a punch biopsy from the perioral region demonstrating acantholytic dyskeratosis consistent with Darier disease. A, 20× magnification. B, 200× magnification.
See this image and copyright information in PMC

References

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    1. Peck G.L., Kraemer K.H., Werzel B., Klingler W.G., Cohen K. Cornifying Darier's disease- A unique variant. Arch Dermatol. 1976;112:495–503. - PubMed

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