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. 2024 Jun;76(3):2906-2909.
doi: 10.1007/s12070-024-04558-2. Epub 2024 Mar 9.

Sublingual Space Schwannoma: An Uncommon Tumour in a Unique Anatomical Location

B I R Davidson  1 , Divya Nayani  1 , Vamshi Krishna Nampally  1 , Rahul Kumar Pitale Ashok  1
Affiliations

Sublingual Space Schwannoma: An Uncommon Tumour in a Unique Anatomical Location

B I R Davidson et al. Indian J Otolaryngol Head Neck Surg. 2024 Jun.

Abstract

A Schwannoma is a benign tumour originating from Schwann cells within the peripheral, cranial, or autonomic nerves. Typically, these tumours manifest as a solitary, slow-growing mass with smooth surface, usually devoid of significant symptoms. Schwannomas most frequently appear in individuals aged 30-50 years. Although they are relatively uncommon, approximately one-fourth of all Schwannomas are found in the head and neck area. Its occurrence within the oral cavity, with the tongue being the most common site, followed by the palate, floor of the mouth, buccal mucosa, lips, and jaws. Diagnosing these tumours before surgery can be challenging, and in most instances, a definitive diagnosis can only be established through surgical intervention and subsequent histological examination. Immunohistochemistry plays a crucial role in confirming the diagnosis, as it shows that Schwannoma cells exhibit a positive reaction to the S-100 protein. Here, we present a case of a Schwannoma in the floor of the mouth, observed in an 18-year-old male patient.

Keywords: Benign tumour; Floor of the mouth; Immunohistochemistry; Schwannoma.

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Conflict of interest statement

Conflict of interestThe authors have disclosed no conflicts of interest.

Figures

Fig. 1
Fig. 1
Shows a mass on the floor of the mouth
Fig. 2
Fig. 2
a, b, c Shows transoral excision of the swelling
Fig. 3
Fig. 3
Histopathological examination of the specimen
Fig. 4
Fig. 4
Immunohistochemical staining shows strong positivity to S-100
See this image and copyright information in PMC

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