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Case Reports
. 2024 Jan-Dec:12:23247096241261322.
doi: 10.1177/23247096241261322.

Is There a Baby in the Lung? A Case of Placental Transmogrification of the Lung

Mohammad Abdulelah  1 , Nicole Kasher  1 , Gabriella Primera  1 , Jessika Matta  1 , Ruchi Patel  2 , Karim Anis  3 , Ernest DiNino  3
Affiliations
Case Reports

Is There a Baby in the Lung? A Case of Placental Transmogrification of the Lung

Mohammad Abdulelah et al. J Investig Med High Impact Case Rep. 2024 Jan-Dec.

Abstract

Pulmonary nodules are commonly encountered in pulmonary practice. Etiologies could include infectious, inflammatory, and malignant. Placental transmogrification of the lung is an extremely rare etiology of pulmonary nodules. Such condition often presents as unilateral lesions in asymptomatic men. In general, such nodules are generally stable and grow extremely slowly. We highlight an unusual case of placental transmogrification of the lung (PLC) identified in a young female. The patient's bilateral nodules were larger than what has been previously cited in the literature and exhibited growth over an 8-year follow-up period.

Keywords: lung nodules; placental transmogrification.

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Conflict of interest statement

Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Axial computed tomography scan of the chest showing a 0.9-cm peripheral lesion.
Figure 2.
Figure 2.
Multiple bilateral nodules, the largest of which is 2.3 cm in the greatest dimension. Notably, the previously seen peripheral nodule has grown and is portraying a more prominent cavitary component.
Figure 3.
Figure 3.
Histopathological observations of the lesion. (A) (40×) presents a broad overview of the lesion, with minimal adjacent lung tissue visible on the right. (B) (100×) reveals the existence of hyaline cartilage (star). (C) (200×) exhibits a close-up view of the lesion, showcasing a fibromyxoid background with structures resembling placental villi (arrow). (D) (100×) demonstrates the presence of trapped respiratory epithelium (arrowhead).
See this image and copyright information in PMC

References

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