doi: 10.1159/000238336.
Inhibitory activity of cefpiramide on beta-lactamase
- PMID: 3888544
- DOI: 10.1159/000238336
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Inhibitory activity of cefpiramide on beta-lactamase
Chemotherapy.
1985.
Abstract
The beta-lactamase stability and inhibitory activity of cefpiramide were investigated. Cefpiramide was found to be stable to hydrolysis and inhibited beta-lactamase produced by Citrobacter freundii, Enterobacter cloacae, Morganella morganii, and Escherichia coli. Kinetic studies showed that cefpiramide is a competitive inhibitor of cephaloridine hydrolysis by E. cloacae beta-lactamase.
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