Barriers and enablers to the effective implementation of omics research in low- and middle-income countries

Jacus S Nacis^#^{1

2}, Patrick Kamande^#^{2

3}, Alemayehu Teklu Toni^{2

4}, Evans Mudibo^{2

5

6}, Robert Musyimi⁶, Siam Popluechai⁷, Trenton Dailey-Chwalibóg^{8

9}, Wieger Voskuijl^{5

10

11

12}, Genevieve Dable-Tupas¹³, Abu Sadat Mohammad Sayeem Bin Shahid¹⁴, Neil Andrew Bascos^{15

16}, Farzana Afroze¹⁴, Mohammod Jobayer Chisti¹⁴, Benson Singa¹⁷, Moses Ngari^{5

6}, Caroline Tigoi^{5

6}, Gomezgani Mhango¹⁸, Harry Freitag¹⁹, Isabel Potani^{5

20

21}, John Mukisa^{5

22}, Amir Kirolos^{23

24}, Kuda Mutasa²⁵, Lionel Olivier Ouédraogo^{9

26}, Andrew M Prentice²⁷, Tsinuel Girma²⁸, Andrew J Prendergast^{25

29}, James Njunge^{5

6}, Paul Kelly^{29

30}, James A Berkley^{5

6

31}, Kirkby Daniel Tickell^{5

32}, Gerard Bryan Gonzales^{33

34

35

36

37}

Affiliations

¹ Department of Science and Technology - Food and Nutrition Research Institute (DOST-FNRI), Taguig, Philippines.
² Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, Netherlands.
³ Department of Food, Nutrition & Dietetics, Kenyatta University, Nairobi, Kenya.
⁴ Department of Pediatrics and Child Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
⁵ The Childhood Acute Illness & Nutrition (CHAIN) Network, Nairobi, Kenya.
⁶ KEMRI/Wellcome Trust Collaborative Research Programme, Kilifi, Kenya.
⁷ School of Science, Mae Fah Luang University, Chiang Rai, Thailand.
⁸ Department of Food Technology, Safety, and Health, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
⁹ Agence de Formation de Recherche et d'Expertise en Santé pour l'Afrique (AFRICSanté), Bobo-Dioulasso, Burkina Faso.
¹⁰ Amsterdam UMC, Emma Children's Hospital, Amsterdam, the Netherlands.
¹¹ Amsterdam UMC, Amsterdam Institute for Global Health and Development, Amsterdam, the Netherlands.
¹² Department of Paediatrics and Child Health, Kamuzu University of Health Sciences, Blantyre, Malawi.
¹³ Center for Research and Development and Department of Pharmacology, College of Medicine, Davao Medical School Foundation, Davao City, Philippines.
¹⁴ Nutrition Research Division, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
¹⁵ National Institute of Molecular Biology and Biotechnology, University of the Philippines - Diliman, Quezon City, Philippines.
¹⁶ Protein, Proteomics and Metabolomics Facility, Philippine Genome Center, University of the Philippines System, Quezon City, Philippines.
¹⁷ Center for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
¹⁸ Training and Research Unit of Excellence, Blantyre, Malawi.
¹⁹ Department of Nutrition and Health and Center for Health and Human Nutrition, FK-KMK, Universitas Gadjah Mada, Yogyakarta, Indonesia.
²⁰ Kamuzu University of Health Sciences, Blantyre, Malawi.
²¹ Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontaria, Canada.
²² Department of Immunology and Molecular Biology, Makerere University, Kampala, Uganda.
²³ Department of Women and Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.
²⁴ Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
²⁵ Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.
²⁶ Centre Muraz, Bobo-Dioulasso, Burkina Faso.
²⁷ MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, Gambia.
²⁸ Department of Pediatrics and Child Health, Jimma University, Jimma, Ethiopia.
²⁹ Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
³⁰ Tropical Gastroenterology and Nutrition Group, Department of Medicine, University of Zambia School of Medicine, Lusaka, Zambia.
³¹ Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
³² Department of Global Health, University of Washington, Seattle, WA, USA.
³³ Department of Science and Technology - Food and Nutrition Research Institute (DOST-FNRI), Taguig, Philippines. bryan.gonzales@ugent.be.
³⁴ Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, Netherlands. bryan.gonzales@ugent.be.
³⁵ The Childhood Acute Illness & Nutrition (CHAIN) Network, Nairobi, Kenya. bryan.gonzales@ugent.be.
³⁶ Center for Research and Development and Department of Pharmacology, College of Medicine, Davao Medical School Foundation, Davao City, Philippines. bryan.gonzales@ugent.be.
³⁷ Department of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium. bryan.gonzales@ugent.be.

^# Contributed equally.

PMID: 38886608
DOI: 10.1038/s41587-024-02274-4

Barriers and enablers to the effective implementation of omics research in low- and middle-income countries

Jacus S Nacis et al. Nat Biotechnol. 2024 Jun.

. 2024 Jun;42(6):988-991.

doi: 10.1038/s41587-024-02274-4.

Authors

Affiliations

¹ Department of Science and Technology - Food and Nutrition Research Institute (DOST-FNRI), Taguig, Philippines.
² Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, Netherlands.
³ Department of Food, Nutrition & Dietetics, Kenyatta University, Nairobi, Kenya.
⁴ Department of Pediatrics and Child Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
⁵ The Childhood Acute Illness & Nutrition (CHAIN) Network, Nairobi, Kenya.
⁶ KEMRI/Wellcome Trust Collaborative Research Programme, Kilifi, Kenya.
⁷ School of Science, Mae Fah Luang University, Chiang Rai, Thailand.
⁸ Department of Food Technology, Safety, and Health, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
⁹ Agence de Formation de Recherche et d'Expertise en Santé pour l'Afrique (AFRICSanté), Bobo-Dioulasso, Burkina Faso.
¹⁰ Amsterdam UMC, Emma Children's Hospital, Amsterdam, the Netherlands.
¹¹ Amsterdam UMC, Amsterdam Institute for Global Health and Development, Amsterdam, the Netherlands.
¹² Department of Paediatrics and Child Health, Kamuzu University of Health Sciences, Blantyre, Malawi.
¹³ Center for Research and Development and Department of Pharmacology, College of Medicine, Davao Medical School Foundation, Davao City, Philippines.
¹⁴ Nutrition Research Division, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
¹⁵ National Institute of Molecular Biology and Biotechnology, University of the Philippines - Diliman, Quezon City, Philippines.
¹⁶ Protein, Proteomics and Metabolomics Facility, Philippine Genome Center, University of the Philippines System, Quezon City, Philippines.
¹⁷ Center for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
¹⁸ Training and Research Unit of Excellence, Blantyre, Malawi.
¹⁹ Department of Nutrition and Health and Center for Health and Human Nutrition, FK-KMK, Universitas Gadjah Mada, Yogyakarta, Indonesia.
²⁰ Kamuzu University of Health Sciences, Blantyre, Malawi.
²¹ Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontaria, Canada.
²² Department of Immunology and Molecular Biology, Makerere University, Kampala, Uganda.
²³ Department of Women and Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.
²⁴ Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
²⁵ Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.
²⁶ Centre Muraz, Bobo-Dioulasso, Burkina Faso.
²⁷ MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, Gambia.
²⁸ Department of Pediatrics and Child Health, Jimma University, Jimma, Ethiopia.
²⁹ Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
³⁰ Tropical Gastroenterology and Nutrition Group, Department of Medicine, University of Zambia School of Medicine, Lusaka, Zambia.
³¹ Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
³² Department of Global Health, University of Washington, Seattle, WA, USA.
³³ Department of Science and Technology - Food and Nutrition Research Institute (DOST-FNRI), Taguig, Philippines. bryan.gonzales@ugent.be.
³⁴ Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, Netherlands. bryan.gonzales@ugent.be.
³⁵ The Childhood Acute Illness & Nutrition (CHAIN) Network, Nairobi, Kenya. bryan.gonzales@ugent.be.
³⁶ Center for Research and Development and Department of Pharmacology, College of Medicine, Davao Medical School Foundation, Davao City, Philippines. bryan.gonzales@ugent.be.
³⁷ Department of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium. bryan.gonzales@ugent.be.

^# Contributed equally.

PMID: 38886608
DOI: 10.1038/s41587-024-02274-4

No abstract available

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References

1. GBD 2016 DALYs and HALE Collaborators. Lancet 390, 1260–1344 (2017)..
1. Coates, M. M. et al. PLoS ONE 16, e0253073 (2021). - DOI - PubMed - PMC
1. World Health Organization. Noncommunicable diseases. who.int, https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases (16 September 2023).
1. Kilama, W. L. Acta Trop. 112, S8–S15 (2009). Suppl 1. - DOI - PubMed
1. World Health Organization. Accelerating Access to Genomics for Global Health (WHO, 2022).

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Barriers and enablers to the effective implementation of omics research in low- and middle-income countries

Affiliations

Barriers and enablers to the effective implementation of omics research in low- and middle-income countries

Authors

Affiliations

References

MeSH terms

LinkOut - more resources

Full Text Sources