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. 2024 Jun 17;14(2):e12398.
doi: 10.1002/pul2.12398. eCollection 2024 Apr.

Cardiopulmonary exercise testing and the 2022 definition of pulmonary hypertension

Dirk Habedank  1   2 , Till Ittermann  3 , Sabine Kaczmarek  2 , Beate Stubbe  2 , Alexander Heine  2 , Anne Obst  2 , Ralf Ewert  2
Affiliations

Cardiopulmonary exercise testing and the 2022 definition of pulmonary hypertension

Dirk Habedank et al. Pulm Circ. .

Erratum in

Abstract

Parameters of cardiopulmonary exercise testing significantly discriminate between healthy subjects and patients with pulmonary hypertension (PH), also according to the new 2022 definition of pulmonary hypertension (mean pulmonary arterial pressure mPAP > 20 mmHg). The cut-offs indicating on PH were peakVO2 ≤ 16.7 mL/min/kg (Youden-Index YI = 0.79), petCO2@AT ≤ 34 mmHg (YI = 0.67), and VE/VCO2@AT ≤ 30 (YI = 0.76).

Keywords: VE/VCO2@AT; cardiopulmonary exercise; peakVO2; petCO2@AT; pulmonary hypertension.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Above: petCO2@AT versus VE/VCO2@AT in healthy subjects (black), and in pulmonary hypertension patients according to the 2015 definition (orange) and additionally 2022 definition (blue). Below: Receiver operating characteristics of the three parameters with best discrimination between patients and healthy individuals. petCO2@AT, end‐tidal partial pressure of carbon dioxide at anaerobic threshold; peakVO2, maximum oxygen uptake per minute; VE/VCO2@AT, ventilation to carbon dioxide output ratio at anaerobic threshold.
See this image and copyright information in PMC

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