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Review
. 2024 Jul 21;45(28):2478-2492.
doi: 10.1093/eurheartj/ehae363.

Ventricular septal defect complicating acute myocardial infarction: diagnosis and management. A Clinical Consensus Statement of the Association for Acute CardioVascular Care (ACVC) of the ESC, the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC and the ESC Working Group on Cardiovascular Surgery

Florian Schlotter  1 , Kurt Huber  2 , Christian Hassager  3 , Sigrun Halvorsen  4 , Pascal Vranckx  5   6 , Janine Pöss  1 , Konstantin Krychtiuk  7   8 , Roberto Lorusso  9 , Nikolaos Bonaros  10 , Patrick A Calvert  11 , Matteo Montorfano  12   13 , Holger Thiele  1
Affiliations
Review

Ventricular septal defect complicating acute myocardial infarction: diagnosis and management. A Clinical Consensus Statement of the Association for Acute CardioVascular Care (ACVC) of the ESC, the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC and the ESC Working Group on Cardiovascular Surgery

Florian Schlotter et al. Eur Heart J. .

Abstract

Ventricular septal defects are a rare complication after acute myocardial infarction with a mortality close to 100% if left untreated. However, even surgical or interventional closure is associated with a very high mortality and currently no randomized controlled trials are available addressing the optimal treatment strategy of this disease. This state-of-the-art review and clinical consensus statement will outline the diagnosis, hemodynamic consequences and treatment strategies of ventricular septal defects complicating acute myocardial infarction with a focus on current available evidence and a focus on major research questions to fill the gap in evidence.

Keywords: Device closure; Mechanical circulatory support; Myocardial infarction; Ventricular septal defect.

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