Comparative Study
Inhibition of prolipoprotein signal peptidase by globomycin
- PMID: 3888977
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Comparative Study
Inhibition of prolipoprotein signal peptidase by globomycin
J Biol Chem.
.
Free article
Abstract
Globomycin inhibits the prolipoprotein-specific signal peptidase activity by binding to the enzyme in a noncompetitive manner (Ki = 36 nM). The Km of prolipoprotein signal peptidase for the prolipoprotein substrate is 6 (+/- 1) microM.
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