Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Anna-Leigh Brown^#¹, Oscar G Wilkins^#^{1

2}, Matthew J Keuss^#¹, Sarah E Kargbo-Hill^#³, Matteo Zanovello¹, Weaverly Colleen Lee¹, Alexander Bampton^{4

5}, Flora C Y Lee^{1

2}, Laura Masino², Yue A Qi⁶, Sam Bryce-Smith¹, Ariana Gatt^{4

5}, Martina Hallegger^{1

2}, Delphine Fagegaltier⁷, Hemali Phatnani⁷; NYGC ALS Consortium; Jia Newcombe⁸, Emil K Gustavsson^{4

9}, Sahba Seddighi^{3

10}, Joel F Reyes³, Steven L Coon¹¹, Daniel Ramos^{3

6}, Giampietro Schiavo^{1

12}, Elizabeth M C Fisher¹, Towfique Raj^{13

14

15

16}, Maria Secrier¹⁷, Tammaryn Lashley^{4

5}, Jernej Ule^{1

2

18}, Emanuele Buratti¹⁹, Jack Humphrey^{13

14

15

16}, Michael E Ward²⁰, Pietro Fratta²¹

Collaborators, Affiliations

Collaborators

NYGC ALS Consortium:
Hemali Phatnani, Justin Kwan, Dhruv Sareen, James R Broach, Zachary Simmons, Ximena Arcila-Londono, Edward B Lee, Vivianna M Van Deerlin, Neil A Shneider, Ernest Fraenkel, Lyle W Ostrow, Frank Baas, Noah Zaitlen, James D Berry, Andrea Malaspina, Pietro Fratta, Gregory A Cox, Leslie M Thompson, Steve Finkbeiner, Efthimios Dardiotis, Timothy M Miller, Siddharthan Chandran, Suvankar Pal, Eran Hornstein, Daniel J MacGowan, Terry Heiman-Patterson, Molly G Hammell, Nikolaos A Patsopoulos, Oleg Butovsky, Joshua Dubnau, Avindra Nath, Robert Bowser, Matthew Harms, Eleonora Aronica, Mary Poss, Jennifer Phillips-Cremins, John Crary, Nazem Atassi, Dale J Lange, Darius J Adams, Leonidas Stefanis, Marc Gotkine, Robert H Baloh, Suma Babu, Towfique Raj, Sabrina Paganoni, Ophir Shalem, Colin Smith, Bin Zhang, Brent Harris, Iris Broce, Vivian Drory, John Ravits, Corey McMillan, Vilas Menon, Lani Wu, Steven Altschuler, Yossef Lerner, Rita Sattler, Kendall Van Keuren-Jensen, Orit Rozenblatt-Rosen, Kerstin Lindblad-Toh, Katharine Nicholson, Peter Gregersen, Jeong-Ho Lee, Sulev Koks, Stephen Muljo

Affiliations

¹ UCL Queen Square Motor Neuron Disease Centre, Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, UCL, London, UK.
² The Francis Crick Institute, London, UK.
³ National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA.
⁴ Queen Square Brain Bank, UCL Queen Square Institute of Neurology, University College London, London, UK.
⁵ Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
⁶ Center for Alzheimer's and Related Dementias, National Institutes of Health, Bethesda, MD, USA.
⁷ Center for Genomics of Neurodegenerative Disease, New York Genome Center (NYGC), New York, NY, USA.
⁸ NeuroResource, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, London, UK.
⁹ Great Ormond Street Institute of Child Health, Genetics and Genomic Medicine, University College London, London, UK.
¹⁰ Medical Scientist Training Program, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
¹¹ Molecular Genomics Core, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.
¹² UK Dementia Research Institute, University College London, London, UK.
¹³ Nash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
¹⁴ Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
¹⁵ Department of Genetics and Genomic Sciences and Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
¹⁶ Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
¹⁷ Department of Genetics, Evolution and Environment, UCL Genetics Institute, University College London, London, UK.
¹⁸ Department of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia.
¹⁹ Molecular Pathology Lab, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
²⁰ National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA. wardme@nih.gov.
²¹ UCL Queen Square Motor Neuron Disease Centre, Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, UCL, London, UK. p.fratta@ucl.ac.uk.

^# Contributed equally.

PMID: 38890465
PMCID: PMC11236699
DOI: 10.1038/s41586-024-07577-9

Published Erratum

Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Anna-Leigh Brown et al. Nature. 2024 Jul.

. 2024 Jul;631(8020):E7.

doi: 10.1038/s41586-024-07577-9.

Authors

Collaborators

NYGC ALS Consortium:
Hemali Phatnani, Justin Kwan, Dhruv Sareen, James R Broach, Zachary Simmons, Ximena Arcila-Londono, Edward B Lee, Vivianna M Van Deerlin, Neil A Shneider, Ernest Fraenkel, Lyle W Ostrow, Frank Baas, Noah Zaitlen, James D Berry, Andrea Malaspina, Pietro Fratta, Gregory A Cox, Leslie M Thompson, Steve Finkbeiner, Efthimios Dardiotis, Timothy M Miller, Siddharthan Chandran, Suvankar Pal, Eran Hornstein, Daniel J MacGowan, Terry Heiman-Patterson, Molly G Hammell, Nikolaos A Patsopoulos, Oleg Butovsky, Joshua Dubnau, Avindra Nath, Robert Bowser, Matthew Harms, Eleonora Aronica, Mary Poss, Jennifer Phillips-Cremins, John Crary, Nazem Atassi, Dale J Lange, Darius J Adams, Leonidas Stefanis, Marc Gotkine, Robert H Baloh, Suma Babu, Towfique Raj, Sabrina Paganoni, Ophir Shalem, Colin Smith, Bin Zhang, Brent Harris, Iris Broce, Vivian Drory, John Ravits, Corey McMillan, Vilas Menon, Lani Wu, Steven Altschuler, Yossef Lerner, Rita Sattler, Kendall Van Keuren-Jensen, Orit Rozenblatt-Rosen, Kerstin Lindblad-Toh, Katharine Nicholson, Peter Gregersen, Jeong-Ho Lee, Sulev Koks, Stephen Muljo

Affiliations

¹ UCL Queen Square Motor Neuron Disease Centre, Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, UCL, London, UK.
² The Francis Crick Institute, London, UK.
³ National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA.
⁴ Queen Square Brain Bank, UCL Queen Square Institute of Neurology, University College London, London, UK.
⁵ Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
⁶ Center for Alzheimer's and Related Dementias, National Institutes of Health, Bethesda, MD, USA.
⁷ Center for Genomics of Neurodegenerative Disease, New York Genome Center (NYGC), New York, NY, USA.
⁸ NeuroResource, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, London, UK.
⁹ Great Ormond Street Institute of Child Health, Genetics and Genomic Medicine, University College London, London, UK.
¹⁰ Medical Scientist Training Program, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
¹¹ Molecular Genomics Core, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.
¹² UK Dementia Research Institute, University College London, London, UK.
¹³ Nash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
¹⁴ Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
¹⁵ Department of Genetics and Genomic Sciences and Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
¹⁶ Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
¹⁷ Department of Genetics, Evolution and Environment, UCL Genetics Institute, University College London, London, UK.
¹⁸ Department of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia.
¹⁹ Molecular Pathology Lab, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
²⁰ National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA. wardme@nih.gov.
²¹ UCL Queen Square Motor Neuron Disease Centre, Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, UCL, London, UK. p.fratta@ucl.ac.uk.

^# Contributed equally.

PMID: 38890465
PMCID: PMC11236699
DOI: 10.1038/s41586-024-07577-9

No abstract available

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Erratum for

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A.
Brown AL, Wilkins OG, Keuss MJ, Kargbo-Hill SE, Zanovello M, Lee WC, Bampton A, Lee FCY, Masino L, Qi YA, Bryce-Smith S, Gatt A, Hallegger M, Fagegaltier D, Phatnani H; NYGC ALS Consortium; Newcombe J, Gustavsson EK, Seddighi S, Reyes JF, Coon SL, Ramos D, Schiavo G, Fisher EMC, Raj T, Secrier M, Lashley T, Ule J, Buratti E, Humphrey J, Ward ME, Fratta P. Brown AL, et al. Nature. 2022 Mar;603(7899):131-137. doi: 10.1038/s41586-022-04436-3. Epub 2022 Feb 23. Nature. 2022. PMID: 35197628 Free PMC article.

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Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Collaborators

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Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Authors

Collaborators

Affiliations

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