Pyroptosis: palmitoylation regulates GSDMD activation and pore formation
- PMID: 38890512
- PMCID: PMC11442660
- DOI: 10.1038/s41422-024-00988-3
Pyroptosis: palmitoylation regulates GSDMD activation and pore formation
Similar articles
-
Palmitoylation at a conserved cysteine residue facilitates gasdermin D-mediated pyroptosis and cytokine release.Proc Natl Acad Sci U S A. 2024 Jul 16;121(29):e2400883121. doi: 10.1073/pnas.2400883121. Epub 2024 Jul 9. Proc Natl Acad Sci U S A. 2024. PMID: 38980908 Free PMC article.
-
Gasdermin D palmitoylation: to cleave or not to cleave?Trends Immunol. 2024 Jun;45(6):403-405. doi: 10.1016/j.it.2024.05.001. Epub 2024 May 16. Trends Immunol. 2024. PMID: 38760304
-
A palmitoylation-depalmitoylation relay spatiotemporally controls GSDMD activation in pyroptosis.Nat Cell Biol. 2024 May;26(5):757-769. doi: 10.1038/s41556-024-01397-9. Epub 2024 Mar 27. Nat Cell Biol. 2024. PMID: 38538834
-
Emerging roles of palmitoylation in pyroptosis.Trends Cell Biol. 2025 Jun;35(6):500-514. doi: 10.1016/j.tcb.2024.10.005. Epub 2024 Nov 8. Trends Cell Biol. 2025. PMID: 39521664 Review.
-
Controlling pyroptosis through post-translational modifications of gasdermin D.Dev Cell. 2025 Apr 7;60(7):994-1007. doi: 10.1016/j.devcel.2025.02.005. Dev Cell. 2025. PMID: 40199241 Review.
Cited by
-
Functional Materials Targeted Regulation of Gasdermins: From Fundamentals to Functionalities and Applications.Adv Sci (Weinh). 2025 Apr;12(16):e2500873. doi: 10.1002/advs.202500873. Epub 2025 Mar 24. Adv Sci (Weinh). 2025. PMID: 40273335 Free PMC article. Review.
References
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources